Renal and Adrenal Gland Localization of Chronic Myelomonocytic Leukemia Presenting as a Kidney nmor

Abstract

Chronic myelomonocytic leukemia (CMML) is a myelodysplastic syndrome (MDS) characterized by prominent monocytosis and an increase in bone marrow monocyte precursors in addition to dyshaematopoietic features (1). Extrahaematological manifestations including cutaneous, neurologic, and rheumatic symptoms have been recorded in association with CMML. Here, we report the first observation of renal, adrenal and perirenal involvement in CMML which presented as a kidney tumor.

Sonographic findings in a fatal case of transient myeloproliferative disorder

“…2 Although not in the context of TMD, leukemic infiltration of the adrenal glands has been demonstrated in the literature. 6 Given this published evidence for multiorgan involvement in leukemia and lymphoma, we speculate that megakaryoblastic infiltration of the adrenal glands in our case might have …”