Renal Abscess Caused by Salmonella Typhi

Abstract

Salmonella typhi is a true pathogen, which is capable of causing both intestinal and extraintestinal infections. Unusual presentations of Salmonella should always be kept in mind as this organism can cause disease in almost any organ of the body. S. typhi has been reported to cause the life-threatening infections such as meningitis, endocarditis, myocarditis, empyema, and hepatic abscess. Renal involvement by S. typhi is a relatively rare presentation. We report a case of renal abscess caused by S. typhi in an afebrile, 10-year-old child who did not have any clinical history of enteric fever. To our knowledge, this is the first reported case of isolation of S. typhi from the renal abscess, and interestingly this isolate was found to be resistant to quinolones.

Salmonella Renal Abscess in an Immunocompetent Child: Case Report and Literature Review

“…Salmonella (NTS and typhoidal) infection commonly presents as gastroenteritis, invasive infection, or metastatic focal infection, but renal involvement, especially in the form of renal abscess, is rare. 8 - 12 , 15 A retrospective review done in Spain found only 1.4% of all infections due to NTS presenting as UTI. 16 Characteristics of patients with NTS isolated from the urine are summarized in Table 2 .…”

“… 10 - 12 Renal abscesses are generally managed with antibiotics, with concomitant surgical intervention in some cases. 10 - 14 …”

Pyonephrosis caused by Salmonella sp. in a patient with polycystic kidney disease undergoing hemodialysis

“…However, there are reports of bacteria resistance to fluoroquinolones in developing countries. For this reason, treatment with third generation cephalosporins is an adequate alternative in these cases [3,12].…”

“…serotypes pathogenic to human beings, the most common clinical disease being gastroenteritis [1,3]. Nevertheless, infections may occur in other sites out of the gastrointestinal tract, as well as may cause a septicemia [3]. Obstructions to urine drainage, like those caused by calculi, may lead to complications such as pyonephrosis, when urine becomes infected.…”

“…There is a great variety of Salmonella spp. serotypes pathogenic to human beings, the most common clinical disease being gastroenteritis [1,3]. Nevertheless, infections may occur in other sites out of the gastrointestinal tract, as well as may cause a septicemia [3].…”