Removal of toxic metals from sewage sludge by EDTA in a closed-loop washing process

Arteaga, Juan Francisco Morales; Kaurin, Anela; Leštan, Domen

doi:10.1016/j.chemosphere.2022.135917

Cited by 6 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Zn was the main contaminant. The SS also contained 85 and 10,240 mg kg −1 Mn and Fe, respectively, which are not considered TMs but readily chelate with EDTA and are removed by washing SS [35]. The TMs concentration in the soil has been shown to increase linearly with increases in the SS application rate [51].…”

Section: Chemical Properties Of Ssmentioning

confidence: 99%

“…In our previous study, we showed that washing with EDTA is efficient in removing Pb, Zn, Cu, Cr, Mn, and Fe from SS [35]. The novel closed-loop process, in which chelator and washing/rinsing solutions are treated and recycled in a pH gradient, was introduced.…”

Section: Introductionmentioning

confidence: 99%

“…The novel closed-loop process, in which chelator and washing/rinsing solutions are treated and recycled in a pH gradient, was introduced. No wastewater, only solid waste, was generated from the process [35]. However, the composition of SS is very complex and depends on the origin and load of the wastewater and the method of wastewater treatment [36,37].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Removal of Toxic Metals from Sewage Sludge by Acid Hydrolysis Coupled with EDTA Washing in a Closed-Loop Process

Arteaga

Zupanc

Dular

et al. 2023

IJERPH

Self Cite

View full text Add to dashboard Cite

Contamination with toxic metals prevents the use of sewage sludge (SS) as a soil fertilizer. Hydrodynamic cavitation, thermal microwaving, microwave-assisted alkaline, and acid hydrolysis coupled with ethylenediaminetetraacetate (EDTA) washing were tested as a method to remove toxic metals from SS. Acid hydrolysis coupled with EDTA washing was most effective and was used in a closed-loop process based on ReSoil technology. EDTA and process solutions were recycled at a pH gradient of 12.5–2, which was imposed by the addition of quicklime (CaO) and H2SO4. An average of 78%-Pb, 76%-Zn, 1%-Cu, and 17%-Cr were removed from SS in five consecutive batches. No wastewater was generated, only solid waste (40%). The EDTA lost in the process (42%) was resupplied in each batch. In a series of batches, the process solutions retained metal removal efficiency and quality. The treatment removed 70% and 23% of P and N, respectively, from SS and increased the leachability of Zn, Cu, Mn, and Fe in the washed SS by 11.7, 6.8, 1.4, and 5.2 times, respectively. Acid hydrolysis coupled with EDTA washing proved to be a technically feasible, closed-loop process but needs further development to reduce reagent, material, and nutrient loss and to reduce toxic emissions from the washed sludge.

show abstract

Section: Chemical Properties Of Ssmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Removal of Toxic Metals from Sewage Sludge by Acid Hydrolysis Coupled with EDTA Washing in a Closed-Loop Process

Arteaga

Zupanc

Dular

et al. 2023

IJERPH

Self Cite

View full text Add to dashboard Cite

show abstract

“…32,33 This property allows EDTA to rapidly form EDTA-Fe complexes (pK a = 14.3) with intracellular LIP. 34,35 Ebselen (EBS) is a lipid-soluble and lowmolecular-weight selenium organic compound, which has been identified as an effective inhibitor of DMT1 protein. 36−38 The combination of EDTA-mediated stock depletion and EBScaused supply blockage is expected to disable LIP and disrupt iron homeostasis in tumor cells.…”

mentioning

confidence: 99%

“…Ethylenediaminetetraacetic acid (EDTA) is a potent chelator of metal ions that can form stable chelates with most metal ions in a 1:1 ratio. , This property allows EDTA to rapidly form EDTA-Fe complexes (p K a = 14.3) with intracellular LIP. , Ebselen (EBS) is a lipid-soluble and low-molecular-weight selenium organic compound, which has been identified as an effective inhibitor of DMT1 protein. − The combination of EDTA-mediated stock depletion and EBS-caused supply blockage is expected to disable LIP and disrupt iron homeostasis in tumor cells. Compared with the methods of delivering exogenous metal elements as therapeutic agents that inevitably result in the occurrence of “metal pollution” and potentially induce adverse effects, − this design could meet the requirements of effective therapy and desirable biocompatibility.…”

mentioning

confidence: 99%

Metal-Free Nanocomposites with Endogenous Labile Iron Pool Disturbing Capacity for Tumor Therapy through Synergetic Stock Depletion and Supply Blockage Strategy

Zhao,

Chen,

Wang

et al. 2024

ACS Materials Lett.

View full text Add to dashboard Cite

Metal iron plays exceedingly important roles in maintaining normal biological activities and is stored as an intracellular labile iron pool (LIP). Disturbing LIP balance to disorganize physiological reactions holds great promise in tumor therapy yet is still lacking exploration. Herein, a novel synergetic strategy was designed for tumor therapy with high efficacy and biocompatibility, which was realized through the metal-free poly(lactic-co-glycolic acid) (PLGA)-ethylenediaminetetraacetic acid (EDTA)-ebselen (EBS) nanocomposites. After degradation, EDTA chelates Fe2+ to deplete intracellular LIP, and EBS inactivates DMT1 protein to inhibit iron supplementation from extracellular regions. This LIP destruction causes the downregulation of iron–sulfur cluster levels, which compromises mitochondrial energy metabolism and arrests the cell cycle. Effective tumor elimination is achieved under PLGA-EDTA-EBS treatment with negligible side effects. This work presents an effective formulation for tumor therapy through a synergetic stock depletion and supply blockage strategy, thereby providing essential implications for the design of tumor therapeutic methods with minimal biosafety issues.

show abstract

Promoted elimination of metronidazole in ferrous ions activated peroxydisulfate process by gallic acid complexation

et al. 2023

View full text Add to dashboard Cite

Removal of toxic metals from sewage sludge by EDTA in a closed-loop washing process

Cited by 6 publications

References 46 publications

Removal of Toxic Metals from Sewage Sludge by Acid Hydrolysis Coupled with EDTA Washing in a Closed-Loop Process

Removal of Toxic Metals from Sewage Sludge by Acid Hydrolysis Coupled with EDTA Washing in a Closed-Loop Process

Metal-Free Nanocomposites with Endogenous Labile Iron Pool Disturbing Capacity for Tumor Therapy through Synergetic Stock Depletion and Supply Blockage Strategy

Promoted elimination of metronidazole in ferrous ions activated peroxydisulfate process by gallic acid complexation

Contact Info

Product

Resources

About