Removal of Pb (II) from aqueous solutions by new layered double hydroxides adsorbent MgCuCaAl-LDH: Free Gibbs energy, entropy and internal energy studies

Mahmoudi, Souhila; Chemat-Djenni, Z.; Bouguettoucha, Abdallah; Guediri, Abderraouf; Chebli, D.; Gil, A.

doi:10.1016/j.inoche.2022.109910

Cited by 10 publications

(3 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…People can be exposed to lead by breathing in lead-contaminated dust particles or from food, water, and dyestuffs. 20,21…”

Section: Introductionmentioning

confidence: 99%

“…People can be exposed to lead by breathing in leadcontaminated dust particles or from food, water, and dyestuffs. 20,21 Lead poisoning in humans directly affects the nervous system and all organs that the US Environmental Protection Agency and the World Health Organization have specied the maximum allowable concentrations of lead in drinking water as 0.015 mg L −1 and 0.01 mg L −1 , respectively. 22,23 Wastewater treatment has become an industry that contributes to the prevention of environmental pollution.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A high-performance fluorescent hybrid material for fluorometric detection and removal of toxic Pb(ii) ions from aqueous media: performance and challenges

2023

View full text Add to dashboard Cite

show abstract

“…People can be exposed to lead by breathing in lead-contaminated dust particles or from food, water, and dyestuffs. 20,21…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A high-performance fluorescent hybrid material for fluorometric detection and removal of toxic Pb(ii) ions from aqueous media: performance and challenges

2023

View full text Add to dashboard Cite

show abstract

“…In entropic binding the TΔS is larger than the ΔH which results in a negative ΔG. This is generally driven by hydrophobic interactions and forces the molecule out of association with the solvent into the binding pocket, giving more energy to the environment through the interaction (Freire, 2008a;Mahmoudi et al, 2022;Ruben et al, 2006a).…”

Section: Figure 110 -Isothermal Titration Calorimeter (Itc) Setup And...mentioning

confidence: 99%

Novel Strategies for Gold Nanoparticle Based Aptamer Selection

Odey¹

View full text Add to dashboard Cite

While many successful biotechnological tools that enable the sensing of compounds withinenvironmental and biological systems have been produced to date, the rapid detection of smallmolecules in solution remains challenging without the utilisation of highly specialised, expensiveequipment. Aptamers are antibody-like bioreceptors that are generated entirely by in vitro methodologies. Theiruse in biosensors has gained much attention due to the ability to generate them to bind small,sometimes toxic molecules that other bioreceptors are incapable of detecting. Much work has goneinto generating aptamers for such targets, only to find that without drastic modification, many don’tfunction well within the biosensors they were designed for, despite their target molecule bindingcapabilities. In light of these findings, aptamer research has shifted towards producing aptamerswith qualities that make them more functional within their designated biosensing system. The overall aim of this study was to design an aptamer generation protocol using a modifiedapproach to systematic evolution of ligands by exponential enrichment (SELEX) that utilised goldnanoparticles (AuNP) to test its compatibility in a AuNP biosensing assay. The aptamer generatedshould possess the ability detect the small molecule it was generated for. My hypothesis was thatutilizing AuNP in the partitioning stage of the aptamer generation process would result in aptamersthat outperform those generated through traditional methods when implemented in a AuNP sensor. Following lengthy optimisation experiments, a novel SELEX protocol involving AuNP was developedfor the generation of aptamers that bound methamphetamine. Using this methodology, a randomnucleotide library underwent enrichment in five selection rounds. From this, individualoligonucleotide sequences (i.e. aptamer candidates) were selected to undergo characterisation usinga plethora of methods including a AuNP-based assay and isothermal titration calorimetry (ITC). A AuNP-based characterisation assay was first optimised using a previously-publishedmethamphetamine binding aptamer (MS-03) generated using a traditional matrix-based selectionsystem as a tool to screen for successful aptamer candidates. This methodology identified onecandidate (OM5-C6) which exhibited a superior response to methamphetamine in this AuNP assaythan the MS-03 aptamer. The OM5-C6 demonstrated detection of methamphetamine at aconcentration of 2 μM methamphetamine, supporting the hypothesis of the study. Interestingly,despite OM5-C6 having a higher response in the AuNP assay compared to MS-03, it exhibited aweaker affinity for methamphetamine as measured by ITC. This revealed interesting thermodynamicqualities of the aptamer and further supported our hypothesis that the selection method employedshould consider the end use sensing system the aptamer is being designed for. Finally, this novel AuNP SELEX method was used to generate aptamers for two additional butdivergent target molecules, namely glyphosate and the ACE-2 receptor binding domain (RBD) ofSARS-CoV-2 spike protein. Whilst reasonable enrichment of the random library was observedfollowing selection rounds with glyphosate, no glyphosate binding aptamers were identified. Thedirect interactive properties of the peptide, RBD of SARS-CoV-2 spike protein, with AuNP meant thatthis AuNP SELEX method may be unsuitable for all protein target molecules. This PhD study demonstrated the capability of a novel AuNP based SELEX and resulted in thedevelopment of an aptamer capable of binding methamphetamine which demonstrated lowerdetection limits in an AuNP sensor.

show abstract

Study on the adsorption of Ce(III) on phosphonic acid functionalized ZIF-67@SiO2 magnetic porous carbon materials

Xu,

Qin,

Cao

et al. 2024

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

Removal of Pb (II) from aqueous solutions by new layered double hydroxides adsorbent MgCuCaAl-LDH: Free Gibbs energy, entropy and internal energy studies

Cited by 10 publications

References 49 publications

A high-performance fluorescent hybrid material for fluorometric detection and removal of toxic Pb(ii) ions from aqueous media: performance and challenges

A high-performance fluorescent hybrid material for fluorometric detection and removal of toxic Pb(ii) ions from aqueous media: performance and challenges

Novel Strategies for Gold Nanoparticle Based Aptamer Selection

Study on the adsorption of Ce(III) on phosphonic acid functionalized ZIF-67@SiO2 magnetic porous carbon materials

Contact Info

Product

Resources

About