Removal of organic solvents by cryogenic desolvation in inductively coupled plasma mass spectrometry. Invited lecture

Multielement Determination and Lead Isotope Ratio Measurement in Alcoholic Beverages by High–Resolution Inductively Coupled Plasma Mass Spectrometry

“…Although a variety of methods have been suggested in order to reduce these e!ects such as evaporation of the solvent (Greenough et al, 1996) and cryogenic desolvation (Alvest et al, 1994), sample dilution remains an attractive alternative due to low risks for contamination and losses of volatile elements.…”

“…Ethanol is known to cause matrix e!ects in ICP-techniques by carbon deposition on the sample introduction system, plasma instability and signal enhancement for some elements (Lowe and Stahl, 1992;Alvest et al, 1994). Although a variety of methods have been suggested in order to reduce these e!ects such as evaporation of the solvent (Greenough et al, 1996) and cryogenic desolvation (Alvest et al, 1994), sample dilution remains an attractive alternative due to low risks for contamination and losses of volatile elements.…”

A high performance liquid chromatography ? inductively coupled plasma-mass spectrometry interface employing desolvation for speciation studies of platinum in chemotherapy drugs

“…The most promising approach is to produce a desolvated aerosol, followed by the removal of the solvent, to introduce a dry analyte particle into the plasma by using devices such as a thermospray or ultrasonic nebuliser with a membrane desolvator [16,17] or a condenser [18,19]. Alternatively the aerosol can be heated after nebulisation, either in the spray chamber or in a separate chamber followed by condensing the vapour [20][21][22][23][24] or membrane desolvation [25][26][27].…”

A microwave assisted desolvation system based on the use of a TM010 cavity for inductively coupled plasma based analytical techniques

“…Among them, the most common is to keep the walls of the spray chamber at high temperature (a few degrees over solvent boiling point) by means of a heating tape wound around it. 2,3 Aerosol radiative heating has also been used. These devices are, in general, more efficient than conductive heating ones and reduce some of the drawbacks shown by the latter.…”

“…2A-2C, respectively). The aerosol generated by the pneumatic concentric nebulizer (1) (Model TR-30-A3, Meinhard, Santa Ana, CA, USA) is introduced in a quartz spray chamber (2) (inner volume, 52 cm 3 ), vertically placed at the centre of a TM 010 cavity (3). Microwave cavity dimensions were calculated so as to obtain a maximum microwave field in the volume occupied by the spray chamber.…”