Removal of oral lichen planus by CO2 laser

Abstract

The aim of this case report is to present a histologically diagnosed oral lichen planus excised by the CO2 laser. Oral lichen planus is a chronic inflammatory mucocutaneous disease of unknown etiology. Different treatments have been used to manage this condition. A 46 year-old female was referred to the Laser Clinic of the Dental School of the Federal University of Bahia to excise a lesion characterized by white patches on the oral mucosa, which was causing pain and burning sensation and had not respond to treatment with triamcinolone and corticosteroids for 3 months. CO2 laser was used to remove the lesion and the conclusive histopathological diagnosis was oral lichen planus. The patient was followed up over 1 year with no signs of lesion recurrence. The use of the CO2 laser was found to be useful and effective to treat lichen planus.

CO2 laser vaporisation in treating oral lichen planus: A split‐mouth randomised clinical trial

“…In comparison with previous studies, de Magalhaes et al (2011) reported a patient who was not responsive to corticosteroids for 3 months; the patient was then treated with CO 2 laser and showed no recurrence or pain for 1 year of follow‐up. The study by Matsumoto et al (2019), in which nine patients with 11 sites were treated with CO 2 laser vaporisation, showed a significant reduction in pain and TSS score 1 year after irradiation.…”

Prospective Evaluation of Surgical Outcome After Transoral CO2 Laser Resection of Potentially Malignant and Early Oral Malignancy

“…After laser surgery, there is formation of a necrotic zone at the edge of the incision which acts as a scaffolding for re-epithelization. In most of studies, time to re-epithelization ranges between 3 and 6 weeks [11,12]. Laser wounds show delay in inflammation.…”

Learning from clinical phenotypes: Low‐dose biophotonics therapies in oral diseases

“…An association with specific drugs or systemic disorders is well documented, as is its predilection for premalignant transformation (Scully & el-Kom, 1985). There have been many attempts at direct ablation or targeting immune cells in OLP with surgical or excimer lasers, but these have shown limited benefits (de -Junior, Aciole, Santos, dos Santos, & Pinheiro, 2011;Liu, Sun, Yang, & Wang, 2017;Mucke et al, 2015;Trehan & Taylor, 2004). Interestingly, despite any direct correlation of a microbiological aspects in its etiopathology, there are clinical reports on efficacy of aPDT in OLP patients.…”