Removal of normal ovaries in women under age 51 at the time of hysterectomy

Karp, Natalie E.; Fenner, Dee E.; Burgunder-Zdravkovski, Lorraine; Morgan, Daniel M.

doi:10.1016/j.ajog.2015.05.062

Cited by 30 publications

(17 citation statements)

References 23 publications

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“…For women undergoing hysterectomy for benign indications, ovarian conservation has now been suggested as a quality metric. 10 …”

Section: Discussionmentioning

confidence: 99%

“…9,10 For premenopausal women with endometrial cancer, the decision to perform oophorectomy at the time of hysterectomy is further complicated by the potential of the ovaries to harbor occult metastatic disease and provide estrogenic stimulation. To date, observational studies have suggested that ovarian conservation is safe in young women with early-stage endometrial cancer.…”

Section: Introductionmentioning

confidence: 99%

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Utilization and Outcomes of Ovarian Conservation in Premenopausal Women With Endometrial Cancer

Wright

Jorge

Tergas

et al. 2016

Obstetrics &Amp; Gynecology

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Objective To examine the trends in use and safety of ovarian conservation in young women with early-stage endometrial cancer undergoing hysterectomy. Methods We conducted a population-based analysis. The National Cancer Database (NCDB) was used to identify women <50 years of age with stage I endometrioid adenocarcinoma of the endometrium who underwent hysterectomy from 1998–2012. Patients were stratified based on whether they underwent oophorectomy or had ovarian conservation. Multivariable models were used to examine predictors of ovarian conservation and the association between ovarian conservation and survival. Results The cohort of 15,648 women included 1121 (7.2%) who had ovarian conservation and 14,527 (92.8%) who underwent oophorectomy. The rate of ovarian conservation was relatively stable from 6.9% (95% CI, 4.9–9.7%) in 1998 to 7.1% (95% CI, 5.8–8.7%) in 2012 (P=0.91). Ovarian conservation was more commonly performed in younger women, black women, those with low grade and earlier stage tumors, and in women treated at community hospitals. In a multivariable model, ovarian conservation was not independently associated with survival (HR=0.94; 95% CI, 0.65–1.37). Similarly, in a Kaplan-Meier analysis, there was no association between ovarian conservation and survival (P=0.19). Conclusion Ovarian conservation does not adversely affect survival for women with early stage endometrial cancer. Despite the oncologic safety of ovarian conservation, the majority of young women with endometrial cancer still undergo oophorectomy at the time surgery.

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“…For women undergoing hysterectomy for benign indications, ovarian conservation has now been suggested as a quality metric. 10 …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Utilization and Outcomes of Ovarian Conservation in Premenopausal Women With Endometrial Cancer

Wright

Jorge

Tergas

et al. 2016

Obstetrics &Amp; Gynecology

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“…We therefore defined the performance of oophorectomy based on pathology reports as previously defined in Karp et al 16 Women who underwent oophorectomy had pathology reports that indicated incidental ovarian cancer, benign pathology (eg, dermoid, endometrioma, fibroma), or normal ovarian tissue. Women who did not undergo oophorectomy had pathology reports with both endometrium and myometrium described and no mention of ovarian tissue.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of Endometriosis During Abdominal or Laparoscopic Hysterectomy for Chronic Pelvic Pain

Mowers

Lim

Skinner

et al. 2016

Obstetrics &Amp; Gynecology

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“…'nın (24) histerektomi ile birlikte BSO'nun 51 yaşın altında uygulanması ile ilgili yapmış oldukları çalışmada, özellikle 46 yaşın altında hastalarda genetik mutasyon (BRCA1-2) veya endometriozis gibi bir patoloji olmadıkça BSO uygulanmaması gerektiğini vurgulamışlardır. Gereksiz yere yapılacak BSO'nun hastaların seksüel fonksiyon bozuklukları-na, kalp sağlığı, diyabet ve erken mortalite gibi sorunlara yol açacağını belirtmişlerdir.…”

Section: Discussionunclassified

The Evaluation of Clinical Indications, Histopathologic Findings and Surgical Methods Routes for Hysterectomy, A Tertiary Referral Center Experience

Seçkin¹,

Karslı²,

Yücel³

et al. 2015

IKSST

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Removal of normal ovaries in women under age 51 at the time of hysterectomy

Cited by 30 publications

References 23 publications

Utilization and Outcomes of Ovarian Conservation in Premenopausal Women With Endometrial Cancer

Utilization and Outcomes of Ovarian Conservation in Premenopausal Women With Endometrial Cancer

Prevalence of Endometriosis During Abdominal or Laparoscopic Hysterectomy for Chronic Pelvic Pain

The Evaluation of Clinical Indications, Histopathologic Findings and Surgical Methods Routes for Hysterectomy, A Tertiary Referral Center Experience

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