Abstract:We developed the remote selective C–H bromination for the synthesis of C4′‐brominated biarylphosphine oxides using FeBr3 as a brominating reagent. C3′‐Brominated products were obtained in reactions with substrates bearing a 2,4,6‐triisopropyl substituent on the bottom ring. Moreover, direct access to C5‐chlorinated peri‐substituted(1‐naphthalenyl)phosphines is developed using FeCl3 as a chlorinating reagent. These halogenated compounds can be utilized for cross‐coupling reactions to construct functionalized ph… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.