Remote prognosis of preeclampsia in women 25 years old and younger

Carleton, Henry; Forsythe, Alan B.; Flores, Raquel García

doi:10.1016/0002-9378(88)90513-3

Cited by 22 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Women were followed up from three months post-delivery [32,49] to N20 years after delivery [24,38,39,43,50,57,60,62]. Publications included women from Europe [23][24][25][28][29][30][32][33][34]36,38,[41][42][43][45][46][47]49,51,[53][54][55][56][57][58]60,63], North America [31,37,39,40,44,50,59,62], and from other world regions [26,27,35,48,52,…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Effects of preeclampsia and eclampsia on maternal metabolic and biochemical outcomes in later life: a systematic review and meta-analysis

Alonso-Ventura

Pasupuleti³

et al. 2020

Metabolism

View full text Add to dashboard Cite

Objective: To evaluate the association between preeclampsia (PE) and eclampsia (E) on subsequent metabolic and biochemical outcomes. Methods: Systematic review and meta-analysis of observational studies. We searched five engines until November 2018 for studies evaluating the effects of PE/E on metabolic and biochemical outcomes after delivery. PE was defined as presence of hypertension and proteinuria at N20 weeks of pregnancy; controls did not have PE/E. Primary outcomes were blood pressure (BP), body mass index (BMI), metabolic syndrome (MetS), blood lipids and glucose levels. Random effects models were used for meta-analyses, and effects reported as risk difference (RD) or mean difference (MD) and their 95% confidence interval (CI). Subgroup analyses by time of follow up, publication year, and confounder adjustment were performed. Results: We evaluated 41 cohorts including 3300 PE/E and 13,967 normotensive controls. Women were followed up from 3 months after delivery up to 32 years postpartum. In comparison to controls, PE/E significantly increased systolic BP (MD = 8.3 mmHg, 95%CI 6.8 to 9.7), diastolic BP (MD = 6.8 mmHg, 95%CI 5.6 to 8.0), BMI (MD = 2.0 kg/m 2 ; 95%CI 1.6 to 2.4), waist (MD = 4.3 cm, 95%CI 3.1 to 5.5), waist-to-hip ratio (MD = 0.02, 95%CI 0.01 to 0.03), weight (MD = 5.1 kg, 95%CI 2.2 to 7.9), total cholesterol (MD = 4.6 mg/dL, CI 1.5 to 7.7), LDL (MD = 4.6 mg/dL; 95%CI 0.2 to 8.9), triglycerides (MD = 7.7 mg/dL, 95%CI 3.6 to 11.7), glucose (MD = 2.6 mg/dL, 95% CI 1.2 to 4.0), insulin (MD = 19.1 pmol/L, 95%CI 11.9 to 26.2), HOMA-IR index (MD = 0.7, 95%CI 0.2 to 1.2), C reactive protein (MD = 0.05 mg/dL, 95%CI 0.01 to 0.09), and the risks of hypertension (RD = 0.24, 95%CI 0.15 to 0.33) and MetS (RD = 0.11, 95%CI 0.08 to 0.15). Also, PE/E reduced HDL levels (MD = -2.15 mg/dL, 95%CI -3.46 to −0.85). Heterogeneity of effects was high for most outcomes. Risk of bias was moderate across studies. Subgroup analyses showed similar effects as main analyses. Conclusion: Women who had PE/E have worse metabolic and biochemical profile than those without PE/E in an intermediate to long term follow up period.

show abstract

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Effects of preeclampsia and eclampsia on maternal metabolic and biochemical outcomes in later life: a systematic review and meta-analysis

Alonso-Ventura

Pasupuleti³

et al. 2020

Metabolism

View full text Add to dashboard Cite

show abstract

“…Two large systematic meta‐analyses of CV outcomes in women with preeclampsia‐eclampsia have been published. Bellamy et al2 included prospective and retrospective cohort studies from 1960 to December 2006; McDonald et al3 included case‐control and cohort studies of preeclampsia‐eclampsia from 1966 to January 2006 and included many of the same studies 2,3,34–54. Women with preeclampsia had a 3‐ to 4‐fold increased risk of developing hypertension, a 2‐fold risk for ischemic heart disease, and increased stroke risk compared with women without a history of preeclampsia.…”

Section: Hypertensive Pregnancy Disorders and Future Cardiovascular Dmentioning

confidence: 99%

Synthesis, properties, and self‐assembly of poly(benzyl ether)‐b‐polystyrene dendritic–linear polymers

Jiang

Wang

Chen

et al. 2005

J of Applied Polymer Sci

View full text Add to dashboard Cite

Poly(benzyl ether)-b-polystyrene dendriticlinear polymers were successfully synthesized using a dendritic chloric poly(benzyl ether) (G 1 -Cl, G 2 -Cl, and G 3 -Cl) as the macroinitiator through the atom transfer radical polymerization process. The structure and properties of the resultant polymers were characterizated by gel permeation chromatography, 1 H-NMR, Fourier transform IR, thermogravimetric analysis, and differential scanning calorimetry. It was found that the temperature, reaction time, molar ratio of the macroinitiator to styrene, and the generation number of the macroinitiator have significant effects on the molecular weights, conversion, and polydispersities of the resulting polymers. These dendritic-linear block polymers had very good solubility in common organic solvents at room temperature. The terminal group (dendritic segments) of the polymers can affect their thermal stability. These dendriticlinear polymers after self-assembling in selective solvents (chloroform/acetone) formed core-shell micelles.

show abstract

“…Both gestational hypertension and pre-eclampsia or eclampsia may be associated in later life with raised blood pressure7–11 or hypertension12–15 and cardiovascular disease. 16 17 Many of the reported studies have examined only hypertension as an outcome and have been limited by small sample sizes, 7 9–13 15 inappropriate comparison groups, 8 12 15 18 or relatively short follow up.…”

Section: Introductionmentioning

confidence: 99%

Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study

Wilson

2003

BMJ

618

384

View full text Add to dashboard Cite

Objective To examine the association between hypertensive diseases of pregnancy (gestational hypertension and pre-eclampsia) and the development of circulatory diseases in later life. Design Cohort study of women who had pre-eclampsia during their first singleton pregnancy. Two comparison groups were matched for age and year of delivery, one with gestational hypertension and one with no history of raised blood pressure. Setting Maternity services in the Grampian region of Scotland. Participants Women selected from the Aberdeen maternity and neonatal databank who were resident in Aberdeen and who delivered a first, live singleton from 1951 to 1970. Main outcome measures Current vital and cardiovascular health status ascertained through postal questionnaire survey, clinical examination, linkage to hospital discharge, and mortality data. Results There were significant positive associations between pre-eclampsia/eclampsia or gestational hypertension and later hypertension in all measures. The adjusted relative risks varied from 1.13-3.72 for gestational hypertension and 1.40-3.98 for pre-eclampsia or eclampsia. The adjusted incident rate ratio for death from stroke for the pre-eclampsia/eclampsia group was 3.59 (95% confidence interval 1.04 to 12.4). Conclusions Hypertensive diseases of pregnancy seem to be associated in later life with diseases related to hypertension. If greater awareness of this association leads to earlier diagnosis and improved management, there may be scope for reducing a proportion of the morbidity and mortality from such diseases.

show abstract

Remote prognosis of preeclampsia in women 25 years old and younger

Cited by 22 publications

References 6 publications

Effects of preeclampsia and eclampsia on maternal metabolic and biochemical outcomes in later life: a systematic review and meta-analysis

Effects of preeclampsia and eclampsia on maternal metabolic and biochemical outcomes in later life: a systematic review and meta-analysis

Synthesis, properties, and self‐assembly of poly(benzyl ether)‐b‐polystyrene dendritic–linear polymers

Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study

Contact Info

Product

Resources

About