Remission of positive symptoms according to the “remission in Schizophrenia Working Group” criteria: A longitudinal study of cognitive functioning

Braw, Yoram; Sitman, Raquel; Cohen, Mírian; Berger, Uri; Lev‐Ran, Shaul; Segev, Aviv; Bloch, Yuval; Levkovitz, Yechiel

doi:10.1016/j.eurpsy.2012.04.003

Cited by 3 publications

(3 citation statements)

References 33 publications

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“…First, we showed that both at baseline and at follow-up, patients who obtained RSWG remission status functioned better in terms of global functioning, unmet needs and QoL, which is in line with earlier findings and supports the validity of the RSWG remission criteria (Barak and Aizenberg, 2012; Braw et al, 2012; Chang et al, 2012; Ciudad et al, 2009; De Hert et al, 2007; Eberhard et al, 2009; Lambert et al, 2010; Van Os et al, 2006). Another interesting finding was that we found an association between younger age at baseline and remission status at follow-up, indicating that increasing age at study entry is associated with a greater risk not to reach remission.…”

Section: Discussionsupporting

confidence: 90%

Remission criteria and functional outcome in patients with schizophrenia, a longitudinal study

Heering

Janssens

Boyette

et al. 2014

Aust N Z J Psychiatry

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In a large sample of patients with a non-affective psychotic disorder, stable remission or moving into remission over time, based on the RSWG criteria, was associated with a favourable functional outcome and QoL, providing further support for the clinical validity of the RSWG remission criteria. The findings also suggest growing adaptation and self-management over time, despite ongoing difficulties.

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Section: Discussionsupporting

confidence: 90%

Remission criteria and functional outcome in patients with schizophrenia, a longitudinal study

Heering

Janssens

Boyette

et al. 2014

Aust N Z J Psychiatry

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“…Risperidone LAI should be investigated for other recovery aspects of schizophrenia, since patients in RSWG-remission have a better cognitive outcome [ 19 , 20 ] and quality of life [ 21 , 22 ], but may perceive a decreased sense of wellbeing [ 23 ]. In addition, Rocca et al [ 24 ] reported that second generation antipsychotic use predicts better social functioning and better executive functions.…”

Section: Discussionmentioning

confidence: 99%

Schizophrenia-spectrum patients treated with long-acting injectable risperidone in real-life clinical settings: functional recovery in remitted versus stable, non-remitted patients (the EVeREST prospective observational cohort study)

Giraud-Baro¹,

Dassa

Vathaire

et al. 2016

BMC Psychiatry

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BackgroundPrevious studies showed functional improvement in stable patients with schizophrenia treated with risperidone long-acting injection (LAI). We therefore re-investigated functional improvement with risperidone LAI in remitted patients, in comparison with stable patients. The study was conducted in real-life conditions because of the high heterogeneity of the patients’ situations.MethodThis was a multi-centre, prospective observational cohort study involving adult schizophrenia-spectrum chronic patients who were previously treated with risperidone LAI for 6 months. Remission was evaluated using the consensus criteria proposed by the Remission in Schizophrenia Working Group (RSWG). The primary endpoint was global functioning (assessed with the Global Assessment of Functioning scale, GAF) after one year of treatment. Social functioning was a secondary outcome.ResultsThe analysis included 1490 patients. Attrition rate was 9.1 % at the end of the study. 27.7 % of patients were in remission after one year of risperidone LAI treatment. The mean GAF rating score (62.5 ± 1.5) was higher than the cut-off previously used to identify patients with satisfactory functioning (60) and significantly higher than the mean GAF score in stable, non-remitted patients (48.3, p < 0.001). Social functioning was also high in remitted patients (21.0 ± 3.6 vs. 17.2 ± 3.7 in non-remitted patients, p < 0.001).ConclusionThe results clearly show that after one year of treatment with risperidone LAI, RSWG-remitted patients have a high level of global functioning, which is significantly higher than in stable, non-remitted patients. Social functioning was also higher in remitted patients as compared with stable, non-remitted patients.

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“…Five of the studies included participants with a diagnosis of schizophrenia only Braw et al, 2013;Kontis et al, 2013;Pantelis et al, 1997a;, three included a diagnosis of schizophrenia, schizophreniform or schizoaffective disorder Joyce et al, 2002;Leeson et al, 2009a), two included schizophrenia or other non-affective psychotic disorder Fagerlund et al, 2006) and one specified "schizophrenia or non-organic and non-affective psychosis" (Saleem et al, 2013). Of the 11 eligible studies (see Table 1), two included some of the same participants Braw et al, 2013) but the studies were separately analysed as different variables were reported: 5-move variables were reported in one of the studies while composite variables were reported in the other. Another of the eligible studies failed to report thinking latencies and included some data previously reported in a prior study.…”

Section: Selection Of Articlesmentioning

confidence: 99%

More haste less speed: A meta-analysis of thinking latencies during planning in people with psychosis

Watson

Joyce

Fugard

et al. 2017

Psychiatry Research

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Cognitive impairment is a core feature of psychosis, with slowed processing speed thought to be a prominent impairment in schizophrenia and first-episode psychosis. However, findings from the Stockings of Cambridge (SOC) planning task suggest changes in processing speed associated with the illness may include faster responses in early stages of planning, though findings are inconsistent. This review uses meta-analytic methods to assess thinking times in psychosis across the available literature. Studies were identified by searching PubMed, Web of Science and Google Scholar. Eligibility criteria: 1) included a sample of people with non-affective psychosis according to DSM III, DSM IV, DSM V or ICD-10 criteria; 2) employed the SOC task; 3) included a healthy control group; and 4) published in English. We identified 11 studies that employed the SOC task. Results show that people with psychosis have significantly faster initial thinking times than non-clinical participants, but significantly slower subsequent thinking times during problem execution. These findings indicate that differences in processing speed are not limited to slower responses in people with psychosis but may reflect a preference for step-by-step processing rather than planning before task execution. We suggest this style of responding is adopted to compensate for working memory impairment.

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Remission of positive symptoms according to the “remission in Schizophrenia Working Group” criteria: A longitudinal study of cognitive functioning

Cited by 3 publications

References 33 publications

Remission criteria and functional outcome in patients with schizophrenia, a longitudinal study

Remission criteria and functional outcome in patients with schizophrenia, a longitudinal study

Schizophrenia-spectrum patients treated with long-acting injectable risperidone in real-life clinical settings: functional recovery in remitted versus stable, non-remitted patients (the EVeREST prospective observational cohort study)

More haste less speed: A meta-analysis of thinking latencies during planning in people with psychosis

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