Remission from Alcohol Use Disorder among Males in the Lundby Cohort during 1947–1997

Abstract

Background Alcohol use disorders are a major health problem, often with a chronic course. Studies on remission from alcohol use disorders are sparse. Objective The aim of this study was to analyse the rate of remission from AUD and the possible influence of other mental disorders and sociodemographic factors on the remission in the Lundby Cohort. Method Remission from AUD was studied for 312 male subjects in the Lundby Cohort, which was followed for 50 years. Cox regression analyses were used to study the possible influence of sociodemographic variables and other mental disorders on AUD remission. Results In all, 64/312 (21%) subjects achieved remission during the study period. The presence of a severe mental disorder, such as delirium tremens and organic disorders, was related to remission. Blue-collar workers had higher rates of remission than white-collar workers. There was indication that treatment improved the prognosis. Conclusions The overall remission rate was low, but treatment may improve the prognosis. Severe mental disorders, such as delirium tremens and organic disorders as well as being blue-collar rather than white-collar worker, were related to remission.

Epidemiology of Recovery From Alcohol Use Disorder

“…The recovery literature is characterized by a mix of cross-sectional population surveys with short-term retrospective assessments (1 year is typical) and prospective follow-ups of smaller-sized samples of risk groups that, with some notable exceptions, 22 – 24 also had relatively short follow-ups. Use of data from the multiple waves of the NESARC dominates this research literature.…”

“…However, the intervals over which repeated measures are obtained rarely exceed 3 to 5 years, although there are notable exceptions with follow-ups of 8 to 10 years or more. 22 – 24 Following large nationally representative samples for decades would be ideal, but the inevitable limitations on research resources have resulted in a collective body of work that generally comprises large representative studies that are cross-sectional or have short-term (e.g., 1 year) follow-ups. Studies with longer-term follow-ups tend to employ smaller, less representative samples.…”

Review of Factors Affecting Remission in Narcological Patients

“…Однако есть данные, что более длительное употребление ПАВ до момента обращения за лечением и бóльшие объемы употребления в позднем среднем возрасте связаны с более стойкими ремиссиями [4] . В Шведском когортном исследовании 312 мужчин, историю которых прослеживали на протяжении 50 лет, значимыми факторами формирования ремиссии оказались эпизоды delirium tremens в анамнезе и наличие органических расстройств головного мозга [22] .…”

“…Похожие данные о протективной роли более высокого уровня образования в профилактике рецидива АЗ (но, видимо, не других зависимостей [3]) получены и в других исследованиях [25] . С другой стороны, в шведском когортном исследовании высшее образование не играло благоприятной роли, а лучших ремиссий достигали занятые физическим трудом рабочие («синие воротнички») [22], что подтверждается и другими эпидемиологическими исследованиями [3] . Стрессовые события, связанные с профессиональным статусом (потеря работы, поиск работы в течение более чем 1 месяца, конфликт с начальником/коллегой, смена работы или рабочих обязанностей, финансовый кризис, банкротство, неспособность платить по счетам, проблемы с законом), оказывали ожидаемое негативное влияние на тяжесть употребления ПАВ и устойчивость ремиссии [3] .…”

Occupational factors associated with long-term abstinence among persons treated for alcohol dependence: A follow-up study

“…[ 41 42 ] Blue-collar workers had higher remission rates than white-collar workers. [ 43 ] More skilled employees were abstinent from AD in an industrial setting, and the reason for maintaining abstinence was the threat of losing the job. One of the supportive measures responsible for abstinence was management and employee-counselor.…”