Remineralization Potential of Grape Seed Versus Amorphous Calciumphosphate-Nanoparticles on Sound and Caries Affected Dentin

Alrafee, Shaimaa; Niazy, Maha A.; El-yassaky, Mohamed

doi:10.21608/adjg.2017.5263

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…On the other hand, GSE showed the highest percentage increase in dentine radiodensity, this was in accordance with other studies (7,(20)(21)(22) . Which showed that, 6.5% GSE solution increased dentin mechanical properties, microhardness and tensile strength.…”

Section: Discussionsupporting

confidence: 92%

The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract

Khoriba¹,

Niazy²,

Sharkawy³

2022

ADJ-for Girls

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Purpose: To evaluate the effect of Miswak and Grape seed extract (GSE) on enamel and dentine subjected to artificial acid challenge in-vitro. Materials and Methods: A total of thirty sound freshly extracted sound human permanent periodontally affected upper molars were used. 30 enamel specimens were cut from the buccal surface of the teeth and 30 dentin specimens were cut from the cervical root area. All specimens were polished to obtain a flat polished surface. Ethanolic miswak extract was prepared by percolation method. Solutions of 10% ethanolic miswak extract, 6.5% Grape seed extract and 0.05% sodium fluoride were prepared. Specimens were divided into two groups (n=30); enamel and dentin. Each group was further divided into three sub-groups (n=10) according to the material used. Group1; treated with 10% ethanolic miswak extract solution. Group2; treated with 6.5% GSE solution. Group3; treated with 0.05% sodium fluoride solution (positive control). Specimens were individually subjected to alternative treatment/pH cycling regimen for 7 days. Radiodensity (change in mineral content) for each enamel and dentine specimen was assessed before and after pH cycling using digital radiography. Data were statistically analyzed; the significance level was set at p ≤0.05. Results: Miswak and GSE showed a high percent gain in enamel and dentine radiodensity compared to fluoride. Conclusion: Miswak and GSE are beneficial to both enamel and dentin through increasing their resistance to acid attacks.

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Section: Discussionsupporting

confidence: 92%

The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract

Khoriba¹,

Niazy²,

Sharkawy³

2022

ADJ-for Girls

Self Cite

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“…Escribano-Bailon and co-workers 34 Some studies have evaluated the effect of GSE on demineralized dentin 36,29 , but the effect of this agent on the remineralization of enamel defects is not well understood. Using grape seed extract, Alrafee et al 37 could produce remineralization of sound and carious affected dentin of white rabbits. Silva APP et al 38 found that grape seed extract could inhibit demineralization of artificial carious lesions in extracted bovine central incisors, though in a smaller scale compered to fluoride.…”

Section: Groupsmentioning

confidence: 99%

An in vitro comparative evaluation of casein phosphopeptide-amorphous calcium phosphate fluoride, tricalcium phosphate and grape seed extract on remineralization of artificial caries lesion in primary enamel

Desai

Rao

Panwar

et al. 2022

Journal of Clinical Pediatric Dentistry

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Objectives: To evaluate and compare the remineralization potential of casein phosphopeptide-amorphous calcium phosphate fluoride, tricalcium phosphate and grape seed extract on artificial caries lesions in primary enamel. Study design: A sample of 40 non-carious, primary molar teeth was collected and cut in longitudinal sections into three equal halves. Those 120 samples were divided into four equal groups. Group A: Sections treated with casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), Group B: Sections treated with tricalcium phosphate, Group C: Sections treated with grape seed extract Group D: Sections treated with deionized water (control group). Samples were evaluated for change in surface characteristics, mineral content using Scanning electron microscopy-energy dispersive X-ray analysis (SEM-EDX) and microhardness using Vicker’s microhardness tester. Cavitated lesions were evaluated for Cone beam computer tomography to obtain baseline data post remineralization. Results: The reminer-alization potential of grape seed extract was found to be greater compared to tricalcium phosphate followed by CPP-ACPF. Conclusion: All the three groups viz. CPP-ACPF, tricalcium phosphate and grape seed extract showed remineralization under the in vitro pH cycling model, while grape seed extract group showed significantly greater remineralization compared to the CPP-ACPF and tricalcium phosphate groups.

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“…Preparation of artificial caries-affected dentin On each rabbit, the left side prepared cavities on the upper and lower teeth were etched using 37% phosphoric acid (Meta Biomed, Germany) for 30 s followed by rinsing for 30 s to obtain artificial caries-affected dentin (Alrafee et al 2017).…”

Section: In Vivo Studymentioning

confidence: 99%

Re-mineralization potential, shear bond strength and hydration characteristics of experimentally prepared tri-calcium aluminate phase-modified glass ionomer cement on sound and caries-affected dentin (An in vitro/in vivo study)

2021

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Background This study aimed to in vivo and in vitro evaluate the remineralization potential and shear bond strength (SBS) of experimentally prepared tri-calcium aluminate (C3A)-modified glass ionomer cements on sound and artificial caries-affected dentin (CAD). A pure tricalcium aluminate (C3A) phase prepared via solid state reaction at elevated temperature from chemically pure calcium carbonate and alumina, to formulate ceramic composite of composition: 75% C3A, 15% CaSO4·2H2O and 10% Bi2O3. The influence of artificial saliva solution on the hydration characteristics and microstructure of the synthesized composite was investigated by X-ray diffraction (XRD) analysis, FTIR spectral analysis, pH determination and scanning electron microscope (SEM) in comparison with distilled water curing medium. Modified cements of C3A glass ionomers (C3A-CGIC) were prepared by addition of the experimentally prepared C3A to the powder component of the conventical glass ionomer cement (CGIC). Five and 10 wt% of C3A- CGICs powder were prepared and compared to CGIC. Cements were applied in prepared class V cavities in rabbits’ teeth either to sound or artificial CAD. All rabbits were killed after 15 days, and then, Ca and P wt% were evaluated at the cement–dentin interface using Energy-Dispersive X-ray Analysis. Specimens for SBS evaluation were prepared for the tested cements bonded either to sound or artificial CAD, then tested using universal testing machine. Results The XRD results indicate that there is an acceleration effect on the hydration reactions and decrease in the rate of conversion process of C3A phase composite due to the presence of free ions in saliva solution which was emphasized by the results of the IR spectral bands of the hydrated paste samples. The SEM micrographs showed a more-dense microstructure with large accumulations of aluminate hydrate crystals of samples cured under saliva solution. Results of the prepared C3A-CGICs showed that 10wt% C3A-GIC group had the highest statistically significant mean Ca, P wt% and SBS values on CAD compared to 5wt% C3A-GIC and CGIC. Conclusions 10 wt% C3A-GIC has a remineralizing effect on artificial CAD under in vivo conditions, plus its improved bonding to dentin compared to CGIC. Thus, it might be promising restorative/base with advanced remineralization potential and adequate bond strength to both sound dentin and CAD.

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Remineralization Potential of Grape Seed Versus Amorphous Calciumphosphate-Nanoparticles on Sound and Caries Affected Dentin

Cited by 4 publications

References 23 publications

The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract

The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract

An in vitro comparative evaluation of casein phosphopeptide-amorphous calcium phosphate fluoride, tricalcium phosphate and grape seed extract on remineralization of artificial caries lesion in primary enamel

Re-mineralization potential, shear bond strength and hydration characteristics of experimentally prepared tri-calcium aluminate phase-modified glass ionomer cement on sound and caries-affected dentin (An in vitro/in vivo study)

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