Remifentanil PCA in labour

Daly, O.; Kelly, K. P.; McCormack, J. G.; Heidemann, B.

doi:10.1111/anae.12339

Cited by 1 publication

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References 11 publications

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“…There was no significant difference in the pH value and the residual alkali level between the two groups (p > 0.05). Kan et al [5] have proved that remifentanil is easy to pass through the placenta, but it can be quickly metabolized in the fetus without causing neonatal respiratory depression [17]. Nonetheless, the author still suggested that in the application of remifentanil patient-controlled intravenous labor analgesia one should provide perfect fetal monitoring measures and necessary neonatal rescue equipment in the delivery room, which can quickly respond to neonatal asphyxia and resuscitation.…”

Section: Discussionmentioning

confidence: 99%

Clinical study on the effect of remifentanil patient-controlled intravenous labor analgesia compared to patient-controlled epidural labor analgesia

et al. 2023

Ginekol Pol

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Objectives: This study aims to investigate the safety and efficacy of remifentanil for patient-controlled intravenous labor analgesia as an alternative to the patient-controlled epidural labor analgesia. Material and Methods:Out of 453 parturients who volunteered for labor analgesia and were selected as research objects, 407 completed the trial. They were divided into the research group (n = 148) and the control group (n = 259; patient-controlled epidural analgesia). In the research group, the first dose of remifentanil, the background dose and the patient--controlled analgesia (PCA) dose were 0.4 μg/kg, 0.04 μg/min and 0.4 μg/kg, respectively, with a lockout interval of 3 min. The control group was given epidural analgesia. The first dose and background dose were 6-8 mL, and PCA dose and the locking time of analgesia pump were 5 mL and 20 min, respectively. The following indexes of the two groups were observed and recorded: the analgesic and sedative effects on parturient, labor process, forceps delivery, cesarean section rate and adverse reactions, and maternal and neonatal conditions.Results: (1) The onset time of analgesia in the research group was (0.97 ± 0.08) min, which was noticeably shorter than that in the control group ([15.74 ± 1.91] min), with a statistically significant difference (t = -93.979, p = 0.000). (2) There was no significant difference in the labor process, forceps delivery, cesarean section rate and neonatal condition between the two groups (p > 0.05). Conclusions: Remifentanil patient-controlled intravenous labor analgesia has the advantage of rapid onset of labor analgesia. Although its analgesic effect is not as accurate and stable as epidural patient-controlled labor analgesia, it shows a high level of maternal and family satisfaction.

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Section: Discussionmentioning

confidence: 99%

Clinical study on the effect of remifentanil patient-controlled intravenous labor analgesia compared to patient-controlled epidural labor analgesia

et al. 2023

Ginekol Pol

View full text Add to dashboard Cite

show abstract

Remifentanil PCA in labour

Cited by 1 publication

References 11 publications

Clinical study on the effect of remifentanil patient-controlled intravenous labor analgesia compared to patient-controlled epidural labor analgesia

Clinical study on the effect of remifentanil patient-controlled intravenous labor analgesia compared to patient-controlled epidural labor analgesia

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