Remarkable diversity of vomeronasal type 2 receptor (OlfC) genes of basal ray-finned fish and its evolutionary trajectory in jawed vertebrates

Zhang, Zicong; Sakuma, Atsuhiro; Kuraku, Shigehiro; Nikaido, Masato

doi:10.1038/s41598-022-10428-0

Cited by 6 publications

(4 citation statements)

References 55 publications

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“…b, Clade tree generated from (a) with local support values indicated at each node (according to a Shimodaira-Hasegawa test). The V2R gene tree was consistent with previous studies, in particular the one by Zhang et al 109 . As our extensive species sample allowed us to define new clades that were only partially or not at all described in previous studies, we also renamed all these clades.…”

Section: Phylogenetic Comparative Analysessupporting

confidence: 92%

Diversity and evolution of the vertebrate chemoreceptor gene repertoire

Policarpo

Baldwin²,

Casañe

et al. 2023

Preprint

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Chemoreception – the ability to smell and taste – is an essential sensory modality of most animals. The number and type of chemical stimuli that animals can perceive depends primarily on the diversity of chemoreceptors they possess and express. In vertebrates, six families of G protein-coupled receptors form the core of their chemosensory system, the olfactory/pheromone receptor gene families OR, TAAR, V1R and V2R, and the taste receptors T1R and T2R. Here, we provide the most comprehensive study to date of the vertebrate chemoreceptor gene repertoire and its evolutionary history. Through the examination of 2,210 vertebrate genomes, we uncover substantial differences in the number and composition of chemoreceptors across vertebrates. We show that the chemoreceptor gene families are co-evolving, highly dynamic, and characterized by lineage-specific expansions (for example, OR in tetrapods; TAAR, T1R in teleosts; V1R in mammals; V2R, T2R in amphibians) and losses. Overall, amphibians, followed by mammals, are the vertebrate clades with the largest chemoreceptor repertoires. While marine tetrapods feature a convergent reduction of chemoreceptor numbers, the number of OR genes correlates with habitat in mammals and birds and with migratory behavior in birds, and the taste receptor repertoire correlates with diet in mammals and with aquatic environment in fish.

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Section: Phylogenetic Comparative Analysessupporting

confidence: 92%

Diversity and evolution of the vertebrate chemoreceptor gene repertoire

Policarpo

Baldwin²,

Casañe

et al. 2023

Preprint

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show abstract

“…Mean values obtained from biological replicates for each gene were used. A particular V2R gene located outside of the main gene cluster of this family and lacking receptor activity is known to be co-expressed with other V2R genes in previously studied vertebrates [ 43 ]. Accordingly, we identified homolog singletons of this gene with very high expression in our studied fish species.…”

Section: Methodsmentioning

confidence: 99%

Expanded olfactory system in ray-finned fishes capable of terrestrial exploration

Burguera,

Dionigi,

Kverková

et al. 2023

BMC Biol

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Background Smell abilities differ greatly among vertebrate species due to distinct sensory needs, with exceptional variability reported in the number of olfactory genes and the size of the odour-processing regions of the brain. However, key environmental factors shaping genomic and phenotypic changes linked to the olfactory system remain difficult to identify at macroevolutionary scales. Here, we investigate the association between diverse ecological traits and the number of olfactory chemoreceptors in approximately two hundred ray-finned fishes. Results We found independent expansions producing large gene repertoires in several lineages of nocturnal amphibious fishes, generally able to perform active terrestrial exploration. We reinforced this finding with on-purpose genomic and transcriptomic analysis of Channallabes apus, a catfish species from a clade with chemosensory-based aerial orientation. Furthermore, we also detected an augmented information-processing capacity in the olfactory bulb of nocturnal amphibious fishes by estimating the number of cells contained in this brain region in twenty-four actinopterygian species. Conclusions Overall, we report a convergent genomic and phenotypic magnification of the olfactory system in nocturnal amphibious fishes. This finding suggests the possibility of an analogous evolutionary event in fish-like tetrapod ancestors during the first steps of the water-to-land transition, favouring terrestrial adaptation through enhanced aerial orientation.

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“…Mean values obtained from biological replicates for each gene were used. Nevertheless, one particular V2R gene located outside of the main gene cluster of this family and lacking receptor activity is known to be co-expressed with other V2R genes in previously studied vertebrates 32 . Accordingly, we identified homolog singletons of this gene with very high expression in our studied fish species (data not shown).…”

Section: Methodsmentioning

confidence: 99%

Expanded olfactory system in fishes capable of terrestrial exploration

Burguera

Dionigi

Kverková

et al. 2022

Preprint

View full text Add to dashboard Cite

Smell abilities differ greatly among vertebrate species, as reflected by the exceptional size variability of gene families and brain regions involved in odour detection. However, key environmental factors shaping the molecular and phenotypic evolution of the olfactory sensory system remain mostly unknown. Here, we investigate the association between diverse ecological traits and the number of olfactory chemoreceptors in the genomes of more than two hundred ray-finned fishes. We found independent expansions producing large gene repertoires in nocturnal amphibious fishes, generally able to perform active terrestrial exploration. Furthermore, we reinforced this finding with an additional analysis of a clariid species (Channallabes apus), a fish lineage with chemosensory-based aerial orientation. Importantly, we also detected an augmented information-processing capacity in the olfactory bulb of examined nocturnal amphibious species. Overall, we report a convergent magnification of the olfactory system in amphibious fishes potentially enhancing terrestrial orientation, revealing the likelihood of an analogous event in tetrapod ancestors during the water-to-land transition.

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Remarkable diversity of vomeronasal type 2 receptor (OlfC) genes of basal ray-finned fish and its evolutionary trajectory in jawed vertebrates

Cited by 6 publications

References 55 publications

Diversity and evolution of the vertebrate chemoreceptor gene repertoire

Diversity and evolution of the vertebrate chemoreceptor gene repertoire

Expanded olfactory system in ray-finned fishes capable of terrestrial exploration

Expanded olfactory system in fishes capable of terrestrial exploration

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