REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness
Nasrin Mortazavi,
Puneet Talwar,
Ekaterina Koshmanova
et al.
Abstract:ObjectiveAnimal studies established that the locus coeruleus (LC) plays important roles in sleep and wakefulness regulation. Whether it contributes to sleep variability in humans is not yet established. Here, we investigated if thein vivoactivity of the LC is related to the variability in the quality of Rapid Eye Movement (REM) sleep.MethodsWe assessed the LC activity of 34 healthy younger (∼22y) and 18 older (∼61y) individuals engaged in bottom-up and top-down cognitive tasks using 7-Tesla functional Magnetic… Show more
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