Rellenos de polialquilamida en lipodistrofia facial asociada al virus de la inmunodeficiencia humana: complicaciones oftalmológicas

García-Pacheco, S.; Blanco-Rivas, R.; Campos-García, S.

doi:10.1016/j.oftal.2013.01.011

Cited by 1 publication

(1 citation statement)

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“…Generally, the use of Bio-Alcamid as a soft tissue filler has proven to be relatively free of adverse effects in the short term, with complications tending to surface several years after injection [8]. The vast majority of adverse effects associated with Bio-Alcamid is abscess formation [9,10], granulomas [3][4][5], infectious complications [11][12][13], and painful inflammatory nodules [5,14,15]. A late-onset gluteal abscess was reported in one case of Bio-Alcamid use in the buttocks muscle [4].…”

Section: Discussionmentioning

confidence: 99%

Embolization of Bio-Alcamid Gluteal Injections in a Female Patient with Patent Foramen Ovale Leading to ARDS and Embolic Stroke

Bolduc

Abdalla

Choudhry

et al. 2019

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Bio-Alcamid is a non-FDA approved permanent dermal filler with a few known adverse effects including granuloma formation at injection site, skin infections, abscess and painful inflammation. Embolization of Bio-Alcamid has not been reported and likely represents a very rare complication. We present the case of a thirty-one-year-old female who presents with cough, dyspnea, hemoptysis, fever, and pleuritic chest pain several hours after receiving Bio-Alcamid gluteal injections. The patient’s symptoms progress rapidly and, within three days, she develops acute respiratory failure requiring intubation. A chest x-ray consistent with acute respiratory distress syndrome (ARDS) is viewed. Concurrently, a 2D echocardiogram reveals a patent foramen ovale (PFO) and severe pulmonary hypertension. Five weeks after initial presentation to the emergency department, the patient demonstrates flaccid quadriplegia, is poorly responsive when sedation is held, and her CT scan of the brain showed multifocal infarcts involving bilateral cerebral hemispheres. A CT of the abdomen reveals renal and splenic infarcts. This case study presents a rare complication of a nonbiodegradable dermal filler, Bio-Alcamid.

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