Relieving pain in minor aphthous stomatitis by a single session of non-thermal carbon dioxide laser irradiation

Abstract

This randomized controlled clinical trial was designed to evaluate the efficacy of single-session, non-thermal, carbon dioxide (CO(2)) laser irradiation in relieving the pain of minor recurrent aphthous stomatitis (miRAS) as a prototype of painful oral ulcers. Fifteen patients, each with two discrete aphthous ulcers, were included. One of the ulcers was randomly allocated to be treated with CO(2) laser (1 W of power in de-focused continuous mode) and the other one served as a placebo. Before laser irradiation, a layer of transparent, non-anesthetic gel was placed on both the laser lesions and the placebo lesions. The patients were requested to grade their pain on a visual analog scale up to 96 h post-operatively. The reduction in pain scores was significantly greater in the laser group than in the placebo group. The procedure itself was not painful, so anesthesia was not required. Powermetry revealed the CO(2) laser power to be 2-5 mW after passing through the gel, which caused no significant temperature rise or any visual effect of damage to the oral mucosa. Our results showed that a low-intensity, non-thermal, single-session of CO(2) laser irradiation reduced pain in miRAS immediately and dramatically, with no visible side effects.

A clinical efficacy of using CO2 laser irradiating to transparent gel on aphthous stomatitis patients

“…Recently, there were a case report and clinical trials showing benefit of immediate pain relief on aphthous ulcers by using CO2 laser at 0.7 to 1.5 W irradiating to the transparent gel. On the basis of no clinical alteration, this was called the non-thermal CO2 irradiation [4][5][6][7] . By comparison with laser ablation for replacing aphthous ulcer with the lasered wound 1,8) , this technique appeared to be non-invasive.…”

Laser: A revolutionary boon in dentistry

“…These discoveries were like those of a study which was directed by Khademi et al, in which the mending time and agony force were assessed and looked at between a low-level laser gathering and a fake treatment bunch which included separate arrangements of patients. [7,8] De Souza et al led a randomized clinical assessment of LLLT (InGaAlP diode laser, 670 nm, 3 J/cm 2 ) in the treatment of RAS in 15 patients and found that LLLT with a topical steroid diminished agony levels after the principal LLLT session. Be that as it may, the level of decrease was not measurably huge.…”

Longitudinally Excited CO2 Laser

“…At present, a CO2 laser of about 3 W a pulsed CW of (10 -1000 ms and a super pulse of 0.1 -1 ms) is used for the skin treatment such as eliminating a mole, a wart, macule (Gotkin et al, 2009) and wrinkle the aurinasal treatment such as hay fever and allergic rhinitis (Takeno et al, 2009), the eye treatment such as blepharochalasis and droopy eyelid (Rokhsar et al, 2008), and the dental treatment such as section and evaporation of soft tissue, hemostasis, and stomatitis (Zand et al, 2009). The advantages of CO2 laser surgery are alleviation of bleeding, pain and edema, and shortening of operation and recovery time.…”