Reliability of Ultrasound Imaging in Examining Integrity and Inflammation in the Dorsalis Pedis Artery

Boman, Robyn; Penkala, Stefania; Chan, Rosa H.M.; Joshua, Fredrick; Cheung, Roy T.H.

doi:10.1016/j.ultrasmedbio.2023.06.017

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…Whilst parameters #2-4 are not routinely used for ultrasound scanning of small vessel leg arteries, we have previously demonstrated excellent intra-and inter-tester reliability for static bmode ultrasound parameters. 32 However, spectral Doppler (parameter #5) is a routine parameter for the assessment of blood flow, 33,34 the observation and measurement of inflammation (parameter #1) is a new technique and the focus of this study.…”

Section: Methodsmentioning

confidence: 99%

Ultrasound imaging of the dorsalis pedis artery as an early indicator of the precursory changes for rheumatoid vasculitis: A case series

Boman,

Penkala,

Chan

et al. 2023

Australas J Ultrason Med

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IntroductionClinical verification of rheumatoid vasculitis (RV) persists as a mid‐to‐late diagnosis with medical imaging or biopsy. Early and subclinical presentations of RV, in particular, can remain underdiagnosed in the absence of adequate diagnostic testing. In this study, the research demonstrated the precursory changes for RV in patients with rheumatoid arthritis (RA) using non‐invasive ultrasound imaging of a peripheral vessel.MethodSix participants were recruited: three participants with (RA) and three age‐ and gender‐matched healthy controls. All participants completed a Foot Health Survey Questionnaire (FHSQ), and participants with RA completed a Rheumatoid Arthritis Disease Activity Index‐5 (RADAI‐5). Bilateral B‐mode and Doppler ultrasound of the dorsalis pedis artery (DPA) was performed. The degree of inflammation, lumen and artery diameters, lumen diameter‐to‐artery diameter ratio and peak systolic velocity in the proximal DPA were compared between the two groups.ResultsThe mean RADAI‐5 score (5.4 ± 0.8 out of 10) indicated moderate disease activity amongst participants with RA. Inflammation was observed in the DPA wall in all participants with RA, compared to no inflammation observed in the control group (Friedmans two‐way analysis: χ2 = 15.733, P = 0.003). Differences between groups for inflammation, lumen diameter and lumen diameter‐to‐artery diameter ratio were found (P < 0.034), without differences for artery diameter and peak systolic velocity (P > 0.605). DPA wall inflammation did not correlate with FHSQ scores (r = −0.770, P = 0.073).ConclusionDespite moderate RA disease activity, this is the first study to demonstrate the use of ultrasound to observe inflammation in small vessel disease. Our findings suggest ultrasound imaging may be a viable screening tool to demonstrate arterial wall inflammation, indicating the precursory changes of RV.

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Section: Methodsmentioning

confidence: 99%

Ultrasound imaging of the dorsalis pedis artery as an early indicator of the precursory changes for rheumatoid vasculitis: A case series

Boman,

Penkala,

Chan

et al. 2023

Australas J Ultrason Med

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“…We have three distinct examples of this in this AJUM issue: Hosokawa et al 2 . compare the detection of submandibular sialoliths by ultrasound with magnetic resonance imaging (MRI) and computed tomography (CT), while Boman et al 3 . present a small case series demonstrating a potential role for ultrasound to detect small vessel inflammation as a pre‐curser to rheumatic vasculitis.…”

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confidence: 99%

Is research one of your New Year's resolutions?

Whalley

2024

Australas J Ultrason Med

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Identification and Quantification of Precursory Changes of Rheumatoid Vasculitis in the Dorsalis Pedis Artery

Ren,

Boman,

Chan

et al. 2024

Ultrasound in Medicine & Biology

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Reliability of Ultrasound Imaging in Examining Integrity and Inflammation in the Dorsalis Pedis Artery

Cited by 5 publications

References 22 publications

Ultrasound imaging of the dorsalis pedis artery as an early indicator of the precursory changes for rheumatoid vasculitis: A case series

Ultrasound imaging of the dorsalis pedis artery as an early indicator of the precursory changes for rheumatoid vasculitis: A case series

Is research one of your New Year's resolutions?

Identification and Quantification of Precursory Changes of Rheumatoid Vasculitis in the Dorsalis Pedis Artery

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