2001
DOI: 10.1067/moe.2001.112949
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Reliability of toluidine blue application in the detection of oral epithelial dysplasia and in situ and invasive squamous cell carcinomas

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Cited by 137 publications
(107 citation statements)
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“…For example, toluidine blue has been used as a mouth stain for identifying high-risk primary oral premalignant lesions (20)(21)(22). Recently, this dye has been used successfully in clinical studies that have correlated histologic progression with high-risk clinicopathologic molecular patterns (i.e., loss of chromosomal heterozygosity; ref.…”
Section: Introduction: Buccal Cells and Oral Cancermentioning
confidence: 99%
See 1 more Smart Citation
“…For example, toluidine blue has been used as a mouth stain for identifying high-risk primary oral premalignant lesions (20)(21)(22). Recently, this dye has been used successfully in clinical studies that have correlated histologic progression with high-risk clinicopathologic molecular patterns (i.e., loss of chromosomal heterozygosity; ref.…”
Section: Introduction: Buccal Cells and Oral Cancermentioning
confidence: 99%
“…The in vivo and ex vivo strategies are intended to identify the precise location of an oral cancer and thereby enhance the success of different therapies (20)(21)(22). These schemes are not without limitations and challenges.…”
Section: Introduction: Buccal Cells and Oral Cancermentioning
confidence: 99%
“…Staining specificity was 65 % because the inflammatory lesions were eliminated for the first time and restained after 14 days. In lesions without epithelial dysplasia or atypical cells, false positivity was 35 % [65].…”
Section: Reliability Of Toludine Blue Staining In Detection Of Oral Smentioning
confidence: 97%
“…It is also shown that the results of vital tissue staining are not always fully reliable. [10] Punch biopsy can be done but the tissue obtained is usually distorted and insufficient which can give false result. Our study established the fact by showing the disparity in 1 case of punch biopsy out of 2 cases.…”
Section: Discussionmentioning
confidence: 99%