Reliability of plateau pressure during patient-triggered assisted ventilation. Analysis of a multicentre database

Reliability of Respiratory System Compliance Calculation During Assisted Mechanical Ventilation: A Retrospective Study

“…They found a good correlation in P plat and C rs between the two groups. The same correlation has been found recently in 15 subjects (4). In a larger sample, our data show a similar correlation.…”

“…During assisted MV, this measurement is limited because of the possible interference of the patient's muscle contraction (2). However, preliminary data show that a stable plateau pressure (P plat ) allows a reliable assessment of respiratory mechanics (3,4). Data on the reliability of this technique in assessing C rs are still limited, hence we aimed to investigate if a stable P plat for at least 2 seconds during assisted MV can lead to a reliable C rs .…”

Evolution of respiratory system compliance and potential for lung recruitment in COVID-19–induced acute respiratory distress syndrome

“… [33] Although the calculation of respiratory system compliance is feasible in the pressure-support mode, [34] this technique overestimates respiratory system compliance as compared to conventional calculation in controlled ventilation. [35] Therefore, respiratory system compliance reported in the COVID-19 group could have been overestimated at day 7. [33] By contrast, our reported respiratory system compliance was assessed exclusively in patients ventilated in volume-controlled mode, ruling out this potential bias.…”

Is Respiratory System Compliance Calculation During Assisted Mechanical Ventilation Reliable?

“…The authors did not provide an explanation for this observation. Recently; however, Bianchi et al (2) found the same and argued that this might be due to dorsal alveolar recruitment induced by diaphragm activity, but their sample size was too small to draw definitive conclusions.…”

“…The authors reply: W e are very thankful to Roesthuis and van der Hoeven (1) for their interest in our article (2) and the issues raised in their interesting letter. We are happy to provide a response since the topic is of growing interest and clarity is of paramount importance.…”