“…The accuracy and precision of delivered V T with this method remains controversial in smaller infants, especially if the lung compliance is less than that of the ventilator circuit. 45,46 It must be noted that all measurements, irrespective of source, are affected by ETT leaks, humidification, ventilator circuit compliance, and airway secretions. Some centers remove patients from volume-targeted ventilation if the ETT leak is Ͼ 30% or re-intubate with a larger ETT to eliminate the leak, so a volume-targeted mode can be used.…”