Reliability of low-frequency auditory stimulation studies associated with technetium-99m hexamethylpropylene amine oxime single-photon emission tomography

Scao, Y. Le; Jézéquel, J; Robier, A.; Baulieu, Jean-Louis; Turzo, A.; Guias, B.; Morin, P

doi:10.1007/bf00208996

Cited by 5 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A rather uniform bilateral activation of the temporal cortex after pure tones and electrical stimuli, was reported by Le Scao et al (7)(8)(9). On the contrary, PET investigations and previous personal studies with SPET, proved an asymmetrical cortical stimulation, with a statistically significant higher increase in contralateral regions (2)(3)(4)6).…”

Section: T a B mentioning

confidence: 82%

SPET Monitoring of Perfusion Changes in Auditory Cortex following Mono- and Multi-Frequency Stimuli

Paludetti¹,

Nardo²,

Calcagni³

et al. 1996

Nuklearmedizin

View full text Add to dashboard Cite

Summary Aim: In order to assess the relationship between auditory cortex perfusion and the frequency of acoustic stimuli, twenty normally-hearing subjects underwent cerebral SPET. Methods: In 10 patients a multi-frequency stimulus (250-4000 Hz at 40 dB SL) was delivered, while 10 subjects were stimulated with a 500 Hz pure tone at 40 dB SL. The prestimulation SPET was subtracted from poststimulation study and auditory cortex activation was expressed as percent increments. Results: Contralateral cortex was the most active area with multi-frequency and monofrequency stimuli as well. A clear demonstration of a tonotopic distribution of acoustic stimuli in the auditory cortex was achieved. In addition, the accessory role played by homolateral acoustic areas was confirmed. Conclusion: The results of the present research support the hypothesis that brain SPET may be useful to obtain semiquantitative reliable information on low frequency auditory level in profoundly deaf patients. This may be achieved comparing the extension of the cortical areas activated by high-intensity multifrequency stimuli.

show abstract

Section: T a B mentioning

confidence: 82%

SPET Monitoring of Perfusion Changes in Auditory Cortex following Mono- and Multi-Frequency Stimuli

Paludetti¹,

Nardo²,

Calcagni³

et al. 1996

Nuklearmedizin

View full text Add to dashboard Cite

show abstract

“…Various authors have supported the reliability and usefulness of single photon emission tomography (SPET) in investigating auditory cortex activation in normal and hearing-impaired subjects [2,3,6,15,16,21]. In this paper the features of ABI-induced activation of the auditory cortex were studied by means of SPET.…”

Section: Introductionmentioning

confidence: 99%

SPET monitoring of auditory cortex activation by electric stimulation in a patient with auditory brainstem implant

Nardo¹,

Girolamo²,

Giuda

et al. 2001

European Archives of Oto-Rhino-Laryngology

View full text Add to dashboard Cite

Auditory cortex activation following multifrequency acoustic stimulation has been evaluated by means of single photon emission tomography (SPET) in one patient before and after an auditory brainstem implant (ABI). No activation could be observed after acoustic stimulation before ABI. After ABI stimulation in the coronal and axial slices, the activation within the temporal cortex contralateral to the stimulated ear was twice (43.76%) that of normal controls (23.94 +/- 2.74%). This marked difference was not present in other selected cortical auditory areas (homolateral temporal, homolateral and contralateral parietal cortices). The temporal cortex was also examined with six consecutive sagittal slices from 18.75 mm up to 56.25 mm lateral to the midline. A very strong activation (51.20%) compared with that of normal controls (9.94 +/- 7.45%) was detected in the 25.26-mm sagittal slice of the temporal cortex contralateral to the stimulated side. The remaining sagittal slices showed an almost normal post-stimulatory activation. As the 25.26-mm sagittal slice corresponds to the medial part of the auditory temporal cortex, its activation suggests that electrode stimulation is concentrated on the region of the cochlear nucleus in which the neurons that transduce high frequencies are located. SPET can be considered useful, in combination with electric auditory-evoked potentials, to obtain information on ABI placement and function, effectiveness of acoustic stimulation, degree of cortical stimulation and tonotopic spatial distribution of auditory cortex activation.

show abstract

The Functional Anatomy of the Normal Human Auditory System: Responses to 0.5 and 4.0 kHz Tones at Varied Intensities

Lockwood

Salvi²,

Coad³

et al. 1999

Cerebral Cortex

119

View full text Add to dashboard Cite

Most functional imaging studies of the auditory system have employed complex stimuli. We used positron emission tomography to map neural responses to 0.5 and 4.0 kHz sine-wave tones presented to the right ear at 30, 50, 70 and 90 dB HL and found activation in a complex neural network of elements traditionally associated with the auditory system as well as non-traditional sites such as the posterior cingulate cortex. Cingulate activity was maximal at low stimulus intensities, suggesting that it may function as a gain control center. In the right temporal lobe, the location of the maximal response varied with the intensity, but not with the frequency of the stimuli. In the left temporal lobe, there was evidence for tonotopic organization: a site lateral to the left primary auditory cortex was activated equally by both tones while a second site in primary auditory cortex was more responsive to the higher frequency. Infratentorial activations were contralateral to the stimulated ear and included the lateral cerebellum, the lateral pontine tegmentum, the midbrain and the medial geniculate. Contrary to predictions based on cochlear membrane mechanics, at each intensity, 4.0 kHz stimuli were more potent activators of the brain than the 0.5 kHz stimuli.

show abstract

Reliability of low-frequency auditory stimulation studies associated with technetium-99m hexamethylpropylene amine oxime single-photon emission tomography

Cited by 5 publications

References 5 publications

SPET Monitoring of Perfusion Changes in Auditory Cortex following Mono- and Multi-Frequency Stimuli

SPET Monitoring of Perfusion Changes in Auditory Cortex following Mono- and Multi-Frequency Stimuli

SPET monitoring of auditory cortex activation by electric stimulation in a patient with auditory brainstem implant

The Functional Anatomy of the Normal Human Auditory System: Responses to 0.5 and 4.0 kHz Tones at Varied Intensities

Contact Info

Product

Resources

About