Reliability and validity of severity dimensions of psychopathology assessed using the <scp>Structured Clinical Interview</scp> for <scp>DSM‐5</scp> (<scp>SCID</scp>)

Shankman, Stewart A.; Funkhouser, Carter J.; Klein, Daniel N.; Davila, Joanne; Lerner, Debra; Hee, Danelle

doi:10.1002/mpr.1590

Cited by 196 publications

(142 citation statements)

References 32 publications

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“…All of the interview modules were administered during the initial evaluation to assess the exclusion criteria, while the post-intervention evaluation used only the module corresponding to depressive disorders. Among its psychometric properties is a Cronbach's alpha of > 0.80 for all disorders [41].…”

Section: Instrumentsmentioning

confidence: 99%

Analysis of the Components of a Cognitive-Behavioral Intervention for the prevention of Depression Administered via Conference Call to Nonprofessional Caregivers: A Randomized Controlled Trial

Vázquez

López

Torres

et al. 2020

IJERPH

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Effective and accessible interventions for indicated prevention of depression are necessary and lacking, especially for informal caregivers. Although telephone-based interventions could increase the accessibility for caregivers, randomized controlled trials are scarce, with no examination of prevention to date. Moreover, the efficacy of specific therapeutic components in preventive cognitive-behavioral programs is unknown. The main objective of this study was to evaluate the efficacy of a telephone-administered psychological preventive intervention in informal caregivers with high depressive symptoms. A total of 219 caregivers were randomized to a cognitive-behavioral conference call intervention (CBCC, n = 69), a behavioral-activation conference call intervention (BACC, n = 70), or a usual care control group (CG, n = 80). Both interventions consisted of five 90-minute group sessions. At the post-intervention, incidence of depression was lower in CBCC and BACC compared to CG (1.5% and 1.4% vs. 8.8%). Relative risk was 0.17 for the CBCC and 0.16 for the BACC, and the number-needed-to-treat was 14 in both groups. Depressive symptoms were significantly lower in BACC and BACC groups compared to CG (d = 1.16 and 1.29), with no significant differences between CBCC and BACC groups. The conference call intervention was effective in preventing depression and the behavioral-activation component (BACC) was comparable to the CBCC intervention.

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Section: Instrumentsmentioning

confidence: 99%

Analysis of the Components of a Cognitive-Behavioral Intervention for the prevention of Depression Administered via Conference Call to Nonprofessional Caregivers: A Randomized Controlled Trial

Vázquez

López

Torres

et al. 2020

IJERPH

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“…There were no diagnosis-based inclusion criteria; however, participants were required to be between the ages of 18 and 30 and have at least one full biological sibling who was eligible to participate. More detailed information regarding the study's inclusion and exclusion criteria and procedures is available elsewhere (Shankman et al, 2018). To avoid non-independence of observations due to the presence of sibling pairs, we randomly assigned one sibling from each sibling pair to community sample 1 and assigned the other sibling to community sample 2.…”

Section: Participantsmentioning

confidence: 99%

The Replicability and Generalizability of Internalizing Symptom Networks Across Five Samples

Funkhouser¹,

Correa²

2019

Preprint

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The popularity of network analysis in psychopathology research has increased exponentially in recent years. Yet, little research has examined the replicability of cross-sectional psychopathology network models, and those that have used single items for symptoms rather than multi-item scales. The present study therefore examined the replicability and generalizability of regularized partial correlation networks of internalizing symptoms within and across five samples (total N = 2,573) using the Inventory for Depression and Anxiety Symptoms, a factor analytically-derived measure of individual internalizing symptoms. As different metrics may yield different conclusions about the replicability of network parameters, we examined both global and specific metrics of similarity between networks. Correlations within and between nonclinical samples suggested considerable global similarities in network structure (rss = .53-.87) and centrality strength (rss = .37-.86), but weaker similarities in network structure (rss = .36-.66) and centrality (rss = .04-.54) between clinical and nonclinical samples. Global strength (i.e., connectivity) did not significantly differ across all five networks and few edges (0-5.5%) significantly differed between networks. Specific metrics of similarity indicated that, on average, approximately 80% of edges were consistently estimated within and between all five samples. The most central symptom (i.e., dysphoria) was consistent within and across samples, but there were few other matches in centrality rank-order. In sum, there were considerable similarities in network structure, the presence and sign of individual edges, and the most central symptom within and across internalizing symptom networks estimated from nonclinical samples, but global metrics suggested network structure and symptom centrality had weak to moderate generalizability from nonclinical to clinical samples.

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“…This may require substantial modifications to interview measures and longer interviewing times, but will allow researchers to quantify dimensions and assess their hierarchical organization, neither of which is advisable for variables affected by exclusion rules, as these rules usually introduce serious distortions in the data (Kotov, Ruggero, Krueger, Watson, & Zimmerman, 2018). Moreover, skip-out free psychopathology severity dimensions have shown superior validity and reliability over categorical diagnoses derived from the same interview (Shankman et al, 2018).…”

Section: How To Hitop: a Practical Guide For Genetic Studiesmentioning

confidence: 99%

Redefining Phenotypes to Advance Psychiatric Genetics: Implications from Hierarchical Taxonomy of Psychopathology

Waszczuk¹

2018

Preprint

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Genetic discovery in psychiatry and clinical psychology is hindered by suboptimal phenotypic definitions. We argue that the hierarchical, dimensional, and data-driven classification system proposed by the Hierarchical Taxonomy of Psychopathology (HiTOP) consortium provides a more effective approach to identifying genes that underlie mental disorders, and to studying psychiatric etiology, than current diagnostic categories. Specifically, genes are expected to operate at different levels of the HiTOP hierarchy, with some highly pleiotropic genes influencing higher-order psychopathology (e.g. the general factor), whereas other genes conferring more specific risk for individual spectra (e.g. internalizing), subfactors (e.g. fear disorders), or narrow symptoms (e.g. mood instability). We propose that the HiTOP model aligns well with the current understanding of the higher-order genetic structure of psychopathology that has emerged from a large body of family and twin studies. We also discuss the convergence between the HiTOP model and findings from recent molecular studies of psychopathology indicating broad genetic pleiotropy, such as cross-disorder SNP-based shared genetic covariance and polygenic risk scores, and we highlight molecular genetic studies that have successfully redefined phenotypes to enhance precision and statistical power. Finally, we suggest how to integrate a HiTOP approach into future molecular genetic research, including quantitative and hierarchical assessment tools for future data-collection and recommendations concerning phenotypic analyses.

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Reliability and validity of severity dimensions of psychopathology assessed using the Structured Clinical Interview for DSM‐5 (SCID)

Cited by 196 publications

References 32 publications

Analysis of the Components of a Cognitive-Behavioral Intervention for the prevention of Depression Administered via Conference Call to Nonprofessional Caregivers: A Randomized Controlled Trial

Analysis of the Components of a Cognitive-Behavioral Intervention for the prevention of Depression Administered via Conference Call to Nonprofessional Caregivers: A Randomized Controlled Trial

The Replicability and Generalizability of Internalizing Symptom Networks Across Five Samples

Redefining Phenotypes to Advance Psychiatric Genetics: Implications from Hierarchical Taxonomy of Psychopathology

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