Reliability and validity of multi-shot DWI in diagnosis of cervical spondylotic myelopathy: a study based on 3-T MRI

Xu, Ximing; Zhou, Bin; Sun, Kaiqiang; Sun, Jingchuan; Wang, Yuan; Chenglong, Ji; Yuan, Xiaoqiu; Zhang, Peng; Guo, Yongfei; Shi, Guodong; Shi, Jiangang

doi:10.1007/s00586-020-06381-z

Cited by 3 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In ZOOM-DWI technology, ADC value serves as its basic quantitative index, which can be used to describe the velocity and range of diffusion motion of water molecules in different directions in the organizational structure of the DWI sequence. The larger the ADC value is, the stronger the dispersion motion of water molecules is [11]. Since early axon damage in CSM patients will change the direction of water molecules, ZOOM-DWI can provide ideas for the early detection of CSM \* MERGEFORMAT [12].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of cervical spine ZOOM-DWI in cervical spondylotic myelopathy

Li,

Tian,

Zhao

et al. 2024

Eur Spine J

View full text Add to dashboard Cite

Purpose To investigate the clinical application value of the non-shared incentive diffusion imaging technique (ZOOM-DWI) diagnoses of cervical spondylotic myelopathy (CSM). Methods 49 CSM patients who presented from January 2022 to December 2022 were selected as the patient group, and 50 healthy volunteers are recruited as the control group. All subjects underwent conventional MRI and ZOOM-DWI of the cervical spine and neurologic mJOA scores in patients with CSM. The spinal ADC values of segments C2-3, C4-5, C5-6, and C6-7 are measured and analyzed in all subjects, with C5-6 being the most severe level of spinal canal compression in the patient group. In addition, the study also analyzes and compares the relationship between the C5-6 ADC value and mJOA score in the patient group. Results The mean ADC shows no significantly different levels in the control group. Among the ADC values at each measurement level in the patient group, except for C4-5 and C6-7 segments are not statistically significant, the remaining pair-wise comparisons all show statistically significant differences (F = 24.368, p < 0.001). And these individuals have the highest ADC value at C5-6. The C5-6 ADC value in the patient group is significantly higher compared with the ADC value in the control group (t = 9.414, p < 0.001), with statistical significance. The ADC value at the patient stenosis shows a significant negative correlation with the mJOA score (r = −0.493, p < 0.001). Conclusion Cervical ZOOM-DWI can be applied to diagnose CSM, and spinal ADC value can use as reliable imaging data for diagnosing cervical myelopathy.

show abstract

Section: Discussionmentioning

confidence: 99%

Diagnostic value of cervical spine ZOOM-DWI in cervical spondylotic myelopathy

Li,

Tian,

Zhao

et al. 2024

Eur Spine J

View full text Add to dashboard Cite

show abstract

“…Cervical spondylotic myelopathy (CSM) is one of the most common causes of spinal cord injury in adults 1 . CSM is commonly caused by lesions, including vertebral osteophytes, herniated discs, and small joint hyperplasia, that directly compress the spinal cord or affect the blood supply, inducing CSM 1,2 . CSM can be treated conservatively (including neck immobilization, pharmacologic treatments, and physical modalities) or surgically (ventral and dorsal decompression/fusion surgical approach) 3 ; however, conservative treatment is much less effective than surgical treatment 4 .…”

mentioning

confidence: 99%

Predictive Value of the Diffusion Magnetic Resonance Imaging Technique for the Postoperative Outcome of Cervical Spondylotic Myelopathy

Wen

Zhang

et al. 2023

Magnetic Resonance Imaging

View full text Add to dashboard Cite

BackgroundDiffusion magnetic resonsance imaging (dMRI) can potentially predict the postoperative outcome of cervical spondylotic myelopathy (CSM).PurposeTo explore preoperative dMRI parameters to predict the postoperative outcome of CSM through multifactor correlation analysis.Study TypeProspective.PopulationPost‐surgery CSM patients; 102 total, 73 male (52.42 ± 10.60 years old) and 29 female (52.0 ± 11.45 years old).Field Strength/Sequence3.0 T/Turbo spin echo T1/T2‐weighted, T2*‐weighted multiecho gradient echo and dMRI.AssessmentSpinal cord function was evaluated using modified Japanese Orthopedic Association (mJOA) scoring at different time points: preoperative and 3, 6, and 12 months postoperative. Single‐factor correlation and t test analyses were conducted based on fractional anisotropy (FA), mean diffusivity, intracellular volume fraction, isotropic volume fraction, orientation division index, increased signal intensity, compression ratio, age, sex, symptom duration and operation method, and multicollinearity was calculated. The linear quantile mixed model (LQMM) and the linear mixed‐effects regression model (LMER) were used for multifactor correlation analysis using the combinations of the above variables.Statistical TestsDistance correlation, Pearson's correlation, multiscale graph correlation and t tests were used for the single‐factor correlation analyses. The variance inflation factor (VIF) was used to calculate multicollinearity. LQMM and LMER were used for multifactor correlation analyses. P < 0.05 was considered statistically significant.ResultsThe single‐factor correlation between all variables and the postoperative mJOA score was weak (all r < 0.3). The linear relationship was stronger than the nonlinear relationship, and there was no significant multicollinearity (VIF = 1.10–1.94). FA values in the LQMM and LMER models had a significant positive correlation with the mJOA score (r = 5.27–6.04), which was stronger than the other variables.Data ConclusionThe FA value based on dMRI significantly positively correlated with CSM patient postoperative outcomes, helping to predict the surgical outcome and formulate a treatment plan before surgery.Evidence Level1Technical EfficacyStage 2

show abstract