Relevance of Heart Failure in Prevention, Treatment and Prognosis of Ischemic Stroke

Hæusler, Karl Georg; Endres, Matthias; Doehner, Wolfram

doi:10.1055/s-0043-102208

Cited by 2 publications

(2 citation statements)

References 31 publications

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“…Stroke in HF is thought to be caused mostly by a thromboembolic etiology [ 66 ]. Approximately 150 years ago, three conditions (Virchow’s triad: abnormalities of the blood flow, vessel wall, and blood constituents) were mentioned as prerequisites for thrombogenesis.…”

Section: Mechanism Of Stroke In Hfmentioning

confidence: 99%

Heart Failure as a Risk Factor for Stroke

Kim

2018

J Stroke

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Heart failure (HF) is one of the major causes of death worldwide. Despite the high incidence of stroke in patients with HF, there has been a controversy as to whether HF itself is a risk factor for stroke. Recently, there is a great deal of evidence that HF itself increases the risk of stroke. In previous studies, the benefit of warfarin for stroke prevention in patients with HF was offset by the risk of bleeding. In the era of non-vitamin K antagonist oral anticoagulants with low bleeding profiles, we can expect a more effective stroke prevention in patients with HF by selective anticoagulation. The purpose of this review is to describe the relationship between stroke and HF, which could be an unconventional risk factor and a potential intervention target for stroke prevention.

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Section: Mechanism Of Stroke In Hfmentioning

confidence: 99%

Heart Failure as a Risk Factor for Stroke

Kim

2018

J Stroke

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“…There are apparently no published data on the efficacy of stroke unit treatment in HF patients. However, the haemodynamically vulnerable state of HF patients suggests a particular benefit of stroke unit care for patients with HF as they have a particularly high risk for cardiac complications and a higher risk of recurrent stroke 161 …”

Section: Cardiac Complications and Heart Failure Management On The St...mentioning

confidence: 99%

Interaction of heart failure and stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis

Doehner,

Böhm,

Boriani

et al. 2023

European J of Heart Fail

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Heart failure (HF) is a major disease in our society that often presents with multiple comorbidities with mutual interaction and aggravation. The comorbidity of HF and stroke is a high risk condition that requires particular attention to ensure early detection of complications, efficient diagnostic workup, close monitoring, and consequent treatment of the patient. The bi‐directional interaction between the heart and the brain is inherent in the pathophysiology of HF where HF may be causal for acute cerebral injury, and ‐ in turn ‐ acute cerebral injury via imbalanced neural and neurovegetative control of cardiovascular regulation may induce or aggravate HF.The present document represents the consensus view of the ESC Council on Stroke, the Heart Failure Association and the ESC Working Group on Thrombosis to summarize current insights on pathophysiologic interactions of the heart and the brain in the comorbidity of HF and stroke. Principal aspects of diagnostic workup, pathophysiologic mechanisms, complications clinical management in acute conditions and in long‐term care of patients with the comorbidity are presented and state of the art clinical management and current evidence from clinical trials is discussed. Beside the physicians perspective, also the patients values and preferences are taken into account.Interdisciplinary cooperation of cardiologists, stroke specialists, other specialists and primary care physicians is pivotal to ensure optimal treatment in acute events and in continued long‐term treatment of these patients. Key consensus statements are presented in a concise overview on mechanistic insights, diagnostic workup, prevention and treatment to inform clinical acute and continued care of patients with the comorbidity of heart failure and stroke.

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Relevance of Heart Failure in Prevention, Treatment and Prognosis of Ischemic Stroke

Cited by 2 publications

References 31 publications

Heart Failure as a Risk Factor for Stroke

Heart Failure as a Risk Factor for Stroke

Interaction of heart failure and stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis

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