Release profile characteristics of biodegradable-polymer-coated drug particles fabricated by dual-capillary electrospray

Extension of nasal anti-Staphylococcus aureus efficacy of lysostaphin by its incorporation into a chitosan-o/w cream

“…Batch C with 2 and 3.5 mg lysostaphin/g cream had a fast release. The cumulative release reached 101% for 3.5 mg/g-C in ∼ 6 h, while it reached 110% for 2 mg/g-C in ∼ 2 h. One reason was due to their smaller particle size which exhibited a larger interface, and it facilitated the lysostaphin release (Lee et al, 2010). Or it was due to lysostaphin distribution in the chitosan-surfactant complex coating of the particle which facilitated the release of lysostaphin.…”

Advances in drug delivery via electrospun and electrosprayed nanomaterials

“…[34][35][36] Although single-step synthesis of solid particles is considered one of the main advantages of EHDA, a grounded conductive solution can be used as the collector, in case colloidal solutions of particles are required for a particular application. 27,31,37 This method enables integration of probable post electrospraying surface-modification process with a particle-collecting step. 30,[38][39][40] Considering the specific requirements of suitable drugdelivery devices for different diseases and also the wide variety of drug characteristics, such as stability and solubility, various techniques might be needed to desirably incorporate the target therapeutic agent into electrospun nanofibers or electrosprayed particles.…”

Innovative next-generation PLGA microparticles with multifunctional architecture

“…The CES process has been found to be effective not only in the encapsulation of various drugs with different physicochemical properties but also in the manipulation of microsphere morphology. For example, water-soluble macromolecules such as proteins, enzymes, and antibiotics are encapsulated by coaxial electrospraying without losing their integrity [14][15][16].…”