Release of fatty acid-binding protein from isolated rat heart subjected to ischemia and reperfusion or to the calcium paradox

Elevated Levels of Both Cardiomyocyte Membrane and Myofibril Damage Markers Predict Adverse Outcomes in Patients With Chronic Heart Failure

“…21 Its release kinetics are different from those of TnT. In patients with acute myocardial infarction, serum levels of H-FABP return to normal by 24 h after the onset of myocardial infarction, 22 which suggests that H-FABP is rapidly cleared from circulation following leakage from the cytosol.…”

Unbound Free Fatty Acids and Heart-Type Fatty Acid–Binding Protein: Diagnostic Assays and Clinical Applications

“…H-FABP was initially reported to be rapidly released from injured myocardium (50 ). Because of the recent redefinition of MI (51 ), biochemical markers have become even more important for assessment of suspected cardiac ischemia patients with non-ST-segment elevation.…”

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“…It is a powerful regulator of the mitochondrial beta-oxidative system in the heart 9 . It was first noted to be a marker of myocardial infarction (MI) in 1988 [10][11] , it is rapidly released from the cytosol into the circulation after myocardial ischemia and necrosis 12 . H-FABP was shown to be associated with chronic heart failure patients 13 .…”