Release of endogenous γ-aminobutyric acid from vocalization nucleus, the robust nucleus of the archistriatum of zebra finch in vitro

Sakaguchi, Hiroki; Asano, Masaya; Yamamoto, Katsunobu; Saito, Nozomu

doi:10.1016/0006-8993(87)90343-x

Cited by 17 publications

(10 citation statements)

References 16 publications

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“…Nonetheless, it does possess a uniformly scattered population of large GABAergic neurons that are imported from the subpallium, and which appear to be local circuit neurons (Sakaguchi et al, 1987;Müller and Scheich, 1988;Braun et al, 1991;Csillag, 1991;Cobos et al, 2001aCobos et al, , 2001b. The present results also help clarify the nature of some of the subdivisions of the arcopallial-amygdaloid complex (formerly called the archistriatal complex).…”

Section: Telencephalonmentioning

confidence: 53%

The distribution and cellular localization of glutamic acid decarboxylase-65 (GAD65) mRNA in the forebrain and midbrain of domestic chick

Sun

Wang

Laverghetta

et al. 2005

Journal of Chemical Neuroanatomy

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Section: Telencephalonmentioning

confidence: 53%

The distribution and cellular localization of glutamic acid decarboxylase-65 (GAD65) mRNA in the forebrain and midbrain of domestic chick

Sun

Wang

Laverghetta

et al. 2005

Journal of Chemical Neuroanatomy

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“…There is, a priori, no reason to believe that seizures induced by metrazole, a GABA antagonist, should specifically spare the areas of low ZENK induction from physiological activation. There is clear evidence for the presence of GABAergic nerve terminals and somata in all layers of field L (Miiller, 1988) and in song nuclei (including the androgen receptor-containing nuclei; Arnold, 1992, 1994), and of GABA release following stimulation of the song circuit (Sakaguchi et al, 1987). Although it remains a formal possibility that these areas failed to experience significant net depolarization after metrazole, it seems much more likely that these particular neuronal populations simply do not express ZENK following electrical excitation.…”

Section: Discussionmentioning

confidence: 99%

Differential induction of the ZENK gene in the avian forebrain and song control circuit after metrazole‐induced depolarization

Mello

Clayton

1995

J. Neurobiol.

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ZENK is an immediate early gene (IEG) that encodes a transcription factor protein, and its induction has been proposed as a necessary step in the cellular process underlying long-term memory formation. We have previously shown that ZENK is induced in adult songbird brain by the sound of birdsong, but, interestingly, induction did not occur in several areas known to respond to song stimuli. Conceivably, the ZENK gene may be repressed in these areas in adult birds. As a further test of this hypothesis, we administered metrazole, a strong GABAergic antagonist that leads to widespread excitation in the brain. Following metrazole, ZENK mRNA increases more than 10-fold throughout most of the telencephalon in both canaries and zebra finches, and primarily in neurons. In contrast, ZENK induction is much lower or absent in the archistriatum, the primary telencephalic sensory-recipient areas (including auditory field L), and the three telencephalic androgen receptor-containing song nuclei (high vocal center, lateral magnocellular nucleus of the anterior neostriatum, and the robust nucleus of the archistriatum). We did not observe any differences in ZENK induction patterns in juvenile versus adult zebra finches, or fall versus spring male canaries. Together with our previous studies of induction by song, these results suggest that in specific parts of the forebrain, including most of the song control system, IEG expression is subject to different constraints than in the rest of the forebrain. Understanding the molecular basis for this differential gene regulation may prove invaluable in understanding the organization of the song control circuit and the avian telencephalon.

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“…In parasagittal slices of zebra finch brain loaded with tritiated GABA, the orthodromic activation of RA neurons, achieved by applying electrical stimuli dorsal to the nucleus, could evoke an increased release of this inhibitory transmitter (Sakaguchi et al, 1987). In contrast, electrical stimulation rostra1 to RA, which would be expected to activate RA's projection neurons antidromically and thus presumably the feedback inhibitory networks that they are part of, did not increase the amount of GABA released (Sakaguchi et al, 1987). The extremely fast nature of the GABA-mediated IPSPs could serve to sharpen the temporal response properties of RA neurons.…”

Section: L-man and Hvc Provide Pharmacologically Distinct Inputmentioning

confidence: 99%

Synaptic basis for developmental plasticity in a birdsong nucleus

1992

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The development and adult production of birdsong are subserved by specialized brain nuclei, including the robust nucleus of the archistriatum (RA), and its afferents originating in the caudal nucleus of the ventral hyperstriatum (HVc) and the lateral portion of the magnocellular nucleus of the anterior neostriatum (L-MAN). An in vitro brain slice preparation was used to characterize the electrophysiological properties of L-MAN and HVc axonal synapses within RA and to examine how these synaptic connections change during the course of song development. Electrical stimulation of L-MAN and not HVc fibers evoked excitatory synaptic potentials from virtually all RA neurons in brain slices prepared from male and female zebra finches less than 25 d of age. These "L-MAN" EPSPs were blocked substantially by the NMDA receptor antagonist D(-)-2-amino-5-phosphonopentanoic acid (D-APV; 50-100 microM) and by hyperpolarization of the postsynaptic membrane. In contrast, when slices were prepared from male finches greater than 35 d of age, electrical stimulation of the L-MAN and the HVc fiber tracts evoked synaptic responses from over 70% of RA neurons. Although the L-MAN EPSPs resembled those seen in RA before day 25, the "HVc" EPSPs were relatively insensitive to D-APV, but almost completely abolished by 6-cyano-7-nitroquinoxaline-2,3-dione, a non-NMDA glutamate receptor antagonist. These experiments indicate that L-MAN and HVc axons make pharmacologically distinct synapses on the same RA neurons, and that these synapses first form at different stages during development.

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Release of endogenous γ-aminobutyric acid from vocalization nucleus, the robust nucleus of the archistriatum of zebra finch in vitro

Cited by 17 publications

References 16 publications

The distribution and cellular localization of glutamic acid decarboxylase-65 (GAD65) mRNA in the forebrain and midbrain of domestic chick

The distribution and cellular localization of glutamic acid decarboxylase-65 (GAD65) mRNA in the forebrain and midbrain of domestic chick

Differential induction of the ZENK gene in the avian forebrain and song control circuit after metrazole‐induced depolarization

Synaptic basis for developmental plasticity in a birdsong nucleus

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