Release kinetics of tebuconazole from porous hollow silica nanospheres prepared by miniemulsion method

Qian, Kun; Shi, Tianyu; He, Shun; Luo, Laixin; liu, Xili; Cao, Yongsong

doi:10.1016/j.micromeso.2012.10.017

Cited by 61 publications

(48 citation statements)

References 22 publications

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“…The authors encapsulated TEB into self-assembled amphiphilic nanoparticles based on chitosan with branched acrylic monomers (polymethyl methacrylate and hydroxymethyl methacrylate). On the other hand, the values of EE achieved in the present study are considerably higher than the TEB EE in porous silicon nanoparticles, which was no greater than 45% [26]. Thus, polymeric carriers for TEB have better potential than inorganic ones, which is proved by their significantly higher EE.…”

Section: Characterization Of the Microparticlescontrasting

confidence: 57%

“…Moreover, as the TEB loading was increased, the average diameter of microparticles became larger, changing from 41.3 to 71.7 µm ( Table 1). Most of the researchers constructing TEB carriers now aim to produce nano-sized formulations, which would be able to penetrate into plant tissues [25][26]. In the present study, we propose using micro-sized TEB formulations both for preventative application and for treating spore-infected seeds by applying the fertilizer to the soil where seeds are sown.…”

Section: Characterization Of the Microparticlesmentioning

confidence: 99%

See 1 more Smart Citation

Antifungal activity of P3HB microparticles containing tebuconazole

Shershneva

Murueva

Zhila

et al. 2019

Journal of Environmental Science and Health, Part B

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In this study, tebuconazole (TEB)-loaded poly-3-hydroxybutyrate (P3HB)-based microparticles were developed and comprehensively characterized. TEB-loaded microparticles (10, 25, and 50%) were prepared using double emulsification technique. Encapsulation efficiency of TEB varied from 59 to 86%. As the loading amount was increased, the average diameter of microparticles increased too, from 41.3 to 71.7 µm, while zeta potential was not influenced by TEB loading, varying between -32.6 and -35.7 mV. TEB was released gradually from 10, 25, and 50% loaded particles, and over 60 days, 25, 43, and 38%, respectively, of the initially loaded amount was released. The data obtained from in vitro TEB release were fitted to different mathematical models. It was shown that the release profiles of TEB could be best explained by Zero-order, Higuchi models and Hixson-Crowell. The antifungal activity of the P3HB/TEB microparticles against phytopathogenic fungi F. moniliforme and F. solani was comparable to that of the free fungicide. Thus, hydrophobic agrochemicals (TEB) can be effectively encapsulated into P3HB microparticles to construct slow-release formulations.

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Section: Characterization Of the Microparticlescontrasting

confidence: 57%

Section: Characterization Of the Microparticlesmentioning

confidence: 99%

Antifungal activity of P3HB microparticles containing tebuconazole

Shershneva

Murueva

Zhila

et al. 2019

Journal of Environmental Science and Health, Part B

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show abstract

“…7b are 0.36 and 0.34 for pH 8.0 and pH 5.5, respectively, indicating an Quasi-Fickian diffusion mechanism where 5-FU molecules transport through the pores of porous silica carriers without any relevant deformation and stresses during the release process [66][67][68]. These results illustrated that these novel HMSNs exhibit a sustained release due to their mesoporous structure [69][70][71].…”

Section: -Fu Encapsulation and The In Vitro Releasementioning

confidence: 99%

Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery

She

Chen

Velleman

et al. 2015

Journal of Colloid and Interface Science

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“…TEB-related studies were reported in several papers, which showed that tebuconazole could be embedded in microparticles, micelles and microgranules and used as a component of powder systems, based on different materials such as poly(methyl methacrylate) and poly(styrene-co-maleic anhydride), 10 ethyl cellulose 7 and silica nanospheres. 11 Khalikov et al 12 prepared and studied TEB mixtures with water-soluble polymers (arabinogalactan, pectin, cyclodextrin, polyvinylpyrrolidone and hydroxyethyl starch). Those studies described TEB encapsulation efficiency and its release duration and mechanism in laboratory systems such as sterile water and soil.…”

Section: Discussionmentioning

confidence: 99%