Relaxationszeiten des Muskelgewebes nach experimentellen Noxen

Abstract

The proton relaxation times of muscles in the limbs of rats were measured after various types of experimental injury. Abnormalities of perfusion, the effect of histamine and of a non-specific myositis resulted in a significant prolongation of T1 and T2 in in-vitro experiments. It must be remembered that these were serious types of injury. It may be possible to demonstrate less extensive muscle changes by means of MR.

Comparing ultrasonography, magnetic resonance imaging and scintigraphy in evaluating an experimentally induced muscular hematoma

“…About 10% of the tissue water is associated with the extracellular space and has a long T2 relaxation time (24). In less serious injury or inflammation of muscle tissue, longer T2 relaxation time may be explained by a larger extracellular compartment (25). Slow relaxing water in that compartment will become relatively more dominant compared to the faster relaxing water in the myo-plasm, resulting in an apparent longer T 2 relaxation time.…”