“…After identifying the DEGs, we performed a hierarchical cluster analysis with the upregulated and downregulated genes illustrated in a heatmap ( Figure 3 E). Gene counts were log 10 transformed and normalized as Z score. In Figure 3 E, two clusters were clearly displayed; all control groups were in one cluster and the LG-HMF groups in another cluster, which indicates high-intragroup consistency and high-intergroup variability.…”