Relative Efficiency of Active Wave Lengths of Ultraviolet in Activation of 7-Dehydrocholesterol

Bunker, John W. M.; Harris, Robert S.; Mosher, L. Malcolm

doi:10.1021/ja01860a013

Cited by 22 publications

(4 citation statements)

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“…Furthermore, several animal studies indicate that UVC, which should never be used in man, is highly effective in both producing vitamin D and in treating rachitic rats [ 7 ]. Knudson and Benford studied numerous UV wavelengths in rats, finding UVC as effective as any of the UVB wavelengths studied in curing rickets [ 8 ].…”

Section: Commentarymentioning

confidence: 99%

On the epidemiology of influenza: reply to Radonovich et al

Cannell

Zasloff

Garland

et al. 2009

Virol J

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On the epidemiology of influenza: reply to Radonovich LJ, Martinello RA, Hodgson M, Milton DK, Nardell EA. Influenza and ultraviolet germicidal irradiation. Virol J. 2008, 5:149 CommentaryTo the Editor:We thank Radonovich et al [1] for commenting on our paper [2], in which we attempted to use the epidemiology of vitamin D to clarify the manifold mysteries surrounding the epidemiology of influenza. Since our publication, Ginde et al [3] have produced additional evidence in support of our theories. They studied the relationship between 25-hydroxy-vitamin D [25(OH)D] levels and recent upper respiratory tract infections (URI) in 18,883 participants in the Third National Health and Nutrition Examination. Compared to individuals with serum 25-hydroxy-vitamin D levels of > 30 ng/ml, those with levels < 10 ng/ml had 55% higher odds of a recent URI. Furthermore, very recent evidence indicates 25(OH)D levels of even 30 ng/ml often signify chronic substrate starvation [4], thus the full antimicrobial properties of vitamin D may be understated.

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Section: Commentarymentioning

confidence: 99%

On the epidemiology of influenza: reply to Radonovich et al

Cannell

Zasloff

Garland

et al. 2009

Virol J

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“…In 1937 Windaus & Bock isolated 7-dehydrocholesterol from animal skin and Schenk (1937) performed the final identification of vitamin DJ. Other unsaturated sterols beside 7-dehydrocholesterol and ergosterol, such as 7-dehydrositosterol (Wunderlich, 1936) and 7-dehydrostigmasterol (Haselwood, 1939) on irradiation gave rise to products with minor antirachitic potency, but 7-dehydrocholesterol has now been identified convincingly as the major precursor in animals of vitamin D (antirachitic) activity (Bunker et al, 1940).…”

Section: Historical Aspects (I) Early Observations Of the Aetiology Omentioning

confidence: 99%

Vitamin D

MacIntyre

Evans

Larkins

1977

Clinical Endocrinology

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“…The skin of most vertebrates contains the precursor of vitamin D 3 (7-DHC) in the membranes of the deepest cells of the epidermis (Holick et al, 2014). Thus, when the skin is exposed to radiation with a wavelength between 290 and 320 nm (UVB radiation), 7-DHC is converted into pre-vitamin D 3 (Bunker et al, 1940;Chen et al, 2010;. The energy of the photons, when incident on 7-DHC, causes a break in the bond between carbon 9 and carbon 10 of the molecule and an isomerization of the 5,7-diene, forming pre-vitamin D 3 .…”

Section: Acquisition Of Vitamin Dmentioning

confidence: 99%

The lifestyle of the leopard gecko and the importance of ultraviolet radiation, vitamin D and calcium

Franco,

Oliveira,

Patrício

et al. 2023

Vet. stn. (Online)

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The gecko leopard (Eublepharis macularius) was first described in 1854 by British herpetologist Edward Blyth. It is one of the most popular pet lizard species, due to its docile temperament, ease of maintenance and reproduction in captivity, its high longevity and small size, and its beauty and diversity of colours and patterns. Ultraviolet (UV) radiation is an important behavioural regulator. Vitamin D also regulates many fundamental physiological functions in vertebrates, mainly calcium homeostasis. Because of the great diversity of reptile species and the wide range of environmental adaptations, it is important to know the necessities and adaptations of each species regarding UV, vitamin D and calcium requirements. This study provides an overview of the leopard gecko’s lifestyle, and the importance of ultraviolet radiation, vitamin D and calcium for this species.

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Relative Efficiency of Active Wave Lengths of Ultraviolet in Activation of 7-Dehydrocholesterol

Cited by 22 publications

References 0 publications

On the epidemiology of influenza: reply to Radonovich et al

On the epidemiology of influenza: reply to Radonovich et al

Vitamin D

The lifestyle of the leopard gecko and the importance of ultraviolet radiation, vitamin D and calcium

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