Relative ability of aqueous humor from dogs with and without primary angle‐closure glaucoma and ADAMTS10 open‐angle glaucoma to catalyze or inhibit collagenolysis
Stephanie A. Pumphrey,
Christine D. Harman,
Amanda L. Anderson
et al.
Abstract:ObjectiveThe objective of the study was to compare the ability of aqueous humor (AH) from dogs with primary angle‐closure glaucoma (CPACG), companion dogs without overt evidence of CPACG, and Beagles with and without ADAMTS10 open‐angle glaucoma (ADAMTS10‐OAG) to catalyze or inhibit collagenolysis.Animals studiedSeventeen normal pet dogs, 27 dogs with CPACG, 19 Beagles with ADAMTS10‐OAG, and 4 unaffected Beagles.ProceduresA fluorescein‐based substrate degradation assay was used to assess AH proteolytic capacit… Show more
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