Relationships of the Insect-Pathogenic Order Entomophthorales (Zygomycota, Fungi) Based on Phylogenetic Analyses of Nuclear Small Subunit Ribosomal DNA Sequences (SSU rDNA)

Jensen, Annette Bruun; Gargas, Andrea; Eilenberg, Jørgen; Rosendahl, Søren

doi:10.1006/fgbi.1998.1063

Cited by 84 publications

(45 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This result suggests that C. coronatus and C. incongruus share more phylogenetic similarities with each other than with C. lampragues. Nie et al (2012) and Jensen et al (1998), using 18S small-subunit rDNA and 28S rDNA sequences and additional Conidiobolus species, reported that C. coronatus formed a well-supported sister cluster to C. firmipilleus, a finding in agreement with previous studies (Vilela et al 2010). Unfortunately, this phylogenetic study did not include more pathogenic species.…”

Section: Systematic Position and Nomenclaturesupporting

confidence: 86%

Human Fungal Pathogens of Mucorales and Entomophthorales

Mendoza

Vilela

Voelz

et al. 2014

Cold Spring Harbor Perspectives in Medicine

View full text Add to dashboard Cite

In recent years, we have seen an increase in the number of immunocompromised cohorts as a result of infections and/or medical conditions, which has resulted in an increased incidence of fungal infections. Although rare, the incidence of infections caused by fungi belonging to basal fungal lineages is also continuously increasing. Basal fungal lineages diverged at an early point during the evolution of the fungal lineage, in which, in a simplified four-phylum fungal kingdom, Zygomycota and Chytridiomycota belong to the basal fungi, distinguishing them from Ascomycota and Basidiomycota. Currently there are no known human infections caused by fungi in Chytridiomycota; only Zygomycotan fungi are known to infect humans. Hence, infections caused by zygomycetes have been called zygomycosis, and the term "zygomycosis" is often used as a synonym for "mucormycosis." In the four-phylum fungal kingdom system, Zygomycota is classified mainly based on morphology, including the ability to form coenocytic (aseptated) hyphae and zygospores (sexual spores). In the Zygomycota, there are 10 known orders, two of which, the Mucorales and Entomophthorales, contain species that can infect humans, and the infection has historically been known as zygomyEditors:

show abstract

Section: Systematic Position and Nomenclaturesupporting

confidence: 86%

Human Fungal Pathogens of Mucorales and Entomophthorales

Mendoza

Vilela

Voelz

et al. 2014

Cold Spring Harbor Perspectives in Medicine

View full text Add to dashboard Cite

show abstract

“…The P. neoaphidis and Z. radicans proteases group together on a strongly supported branch and form a sister group to a C. coronatus protease. The long branches between the C. coronatus protease and the Pandora/Zoophthora protease group might occur because C. coronatus is among the most basal fungi within the monophyletic order Entomophthorales (Jensen et al, 1998). Together, the entomophthoralean proteases form a sister group to most proteases from ascomycete species, including two proteases from M. anisopliae, but excluding those from Aspergillus species, which form separate groups.…”

Section: Enzymes From Entomophthoralean Fungi Are Uniquementioning

confidence: 99%

Secretome of fungus-infected aphids documents high pathogen activity and weak host response

Grell

Jensen

Olsen

et al. 2011

Fungal Genetics and Biology

Self Cite

View full text Add to dashboard Cite

a b s t r a c tThe discovery of novel secretome proteins can add to our understanding of host-pathogen interactions. Here we report a rich diversity of secreted proteins from the interaction between grain aphids (host, insect order Hemiptera) and fungi of the order Entomophthorales (insect pathogens). The proteins were identified using a unique method unbiased by known sequences or functions to screen a cDNA library constructed directly from field-sampled material. We show for the first time that fungi from the genera Pandora and Entomophthora are armed with a battery of hydrolytic enzymes for penetrating the host cuticle. This enables both access to the hemolymph and exit for sporulation. Further, they secrete enzymes, most notably a number of lipases, for digestion of easily accessible high-energy compounds in the hemolymph. In contrast, we identified only few host genes potentially involved in the interaction, indicating that aphids respond only weakly to the pathogens. These results support recent findings that aphids have a reduced immune repertoire.

show abstract

“…Within the Zygomycota, the entomophthoralean fungi Basidiobolaceae is peculiar in that it possesses a centriolelike organelle with 11-12 microtubules reminiscent of kinetosomes of zoosporic fungi (McKerracher and Heath, 1985). Consistent with this ultrastructural observation, nSSU rDNA analyses suggest that Basidiobolaceae may be nested within the chytrid clade (Jensen et al, 1998;Nagahama et al, 1995). Subsequently, nSSU rDNA (James et al, 2000;Tanabe et al, 2000) analyses, including broader representatives of basal fungi, were unable to resolve the phylogenetic position of Basidiobolaceae.…”

Section: Relationships Within Zygomycotamentioning

confidence: 99%

“…The phylogenetic and taxonomic status of the muco-ralean family Mortierellaceae is problematic because it appeared to be distantly related to the other mucoralean fungi, i.e., it rather clusters with Endogone in several nSSU rDNA studies (Gehrig et al, 1996;Jensen et al, 1998). Besides molecular data, Mortierellacean fungi possess several characteristic phenotypic and biochemical properties that are distinct from other mucoralean fungi: hyaline and smooth zygospores, sporangia without a columella (a structure inside the sporangium that is extended from the sporangiophore), and desmosterol and 24,25-methylene cholesterol as the major sterol components (ergosterol in other mucoralean fungi; see Gandhi, 1997, 1999).…”

Section: Relationships Within Zygomycotamentioning

confidence: 99%

“…Several nSSU rDNA studies have suggested that the Glomales evolved separately from other basal fungal orders, and that it was related to even higher fungi (Bruns et al, 1992;Gehrig et al, 1996;Jensen et al, 1998;Nagahama et al, 1995;Schüßler et al, 2001). From these results, Schüßler et al (2001) revised the higher-level taxonomy of the Glomales: the Glomales (sensu Morton and Benny, 1990) was elevated to the new phylum Glomeromycota, and the four orders, the Archaeosporales, Diversisporales, Glomerales, and Paraglomales were revised or newly erected within the Glomeromycota.…”

Section: Relationships Within Zygomycotamentioning

confidence: 99%

See 1 more Smart Citation

Evolutionary relationships among basal fungi (Chytridiomycota and Zygomycota): Insights from molecular phylogenetics

Tanabe

Watanabe

Sugiyama³

2005

J. Gen. Appl. Microbiol.

View full text Add to dashboard Cite

Evolutionary relationships of the two basal fungal phyla Chytridiomycota and Zygomycota are reviewed in light of recent molecular phylogenetic investigation based on rDNA (nSSU, nLSU rDNA), entire mitochondrial genomes, and nuclear protein coding gene sequences (e.g., EF-1a a, RPB1). Accumulated molecular evidence strongly suggests that the two basal fungal phyla are not monophyletic. For example, the chytridiomycete order Blastocladiales appears to be closely related to the zygomycete order Entomophthorales. Within the Zygomycota, a monophyletic clade, consisting of the Dimargaritales, Harpellales, and Kickxellales, which is characterized by a shared unique septal ultrastructure, was identified. Moreover, evidence for the exclusion of zygomycete orders Amoebidiales and Eccrinales from the Fungi, and their placement at the Animal-Fungi boundary has been clearly documented. Microsporidia, a group of amitochondriate organisms currently under intensive study, is not supported as derived within the Fungi, but a fungal affinity cannot be ruled out. Taking these molecular phylogenetic studies into account, we proposed a hypothetical evolutionary framework of basal fungi.Key Words-Chytridiomycota; Fungi; Microsporidia; molecular phylogeny; nSSU rDNA; RPB1; Zygomycota J. Gen. Appl. Microbiol., 51, 267-276 (2005) Invited Review * Present address, and address reprint requests to: Dr. Junta Sugiyama, TechnoSuruga Co., Ltd. (formerly NCIMB Japan), Tokyo Office, Ogawamachi Kita Bldg. 4F, 1-8-3 Kanda Ogawamachi, Chiyoda-ku, Tokyo 101-0052, Japan. E-mail: jsugiyam@tecsrg.co.jp basal fungal phyla as suggested by accumulating molecular phylogenetic studies, especially emphasizing supra-ordinal relationships. Non-monophyletic nature of ChytridiomycotaCurrently, the Chytridiomycota contains five orders: the Blastocladiales, Chytridiales, Neocallimastigales, Monoblepharidales, and Spizellomycetales (Hawksworth et al., 1995). This classification scheme is based primarily on zoospore ultrastructure (Barr, 1990). Results of molecular phylogenetic analyses of rDNA sequences suggest that the Spizellomycetales, Neocallimastigales, and Monoblepharidales are monophyletic (James et al., 2000;Li and Heath, 1992), supporting the validity of the proposed chytrid higher-level taxonomy. The Chytridiales, however, appears to be polyphyletic as are some chytrid genera (e.g., Rhizophydium; James et al., 2000). rDNA analyses, however, have not resolved the interordinal relationships of the Chytridiomycota, which might be due to the lack of phylogenetic signal within rDNA sequences (James et al., 2000). Although taxon sampling has been limited, analysis of complete mitochondrial genome sequences has provided a clearer framework of chytridiomycete phylogeny. This analysis suggests that the Monoblepharidales branched earlier than a well-supported Chytridiales-Spizellomycetales lineage (Bullerwell et al., 2003a). In the mtDNA analysis, the phylogenetic position of the Blastocladiales is not statistically re- Barr (1980) a This classification sche...

show abstract

Relationships of the Insect-Pathogenic Order Entomophthorales (Zygomycota, Fungi) Based on Phylogenetic Analyses of Nuclear Small Subunit Ribosomal DNA Sequences (SSU rDNA)

Cited by 84 publications

References 30 publications

Human Fungal Pathogens of Mucorales and Entomophthorales

Human Fungal Pathogens of Mucorales and Entomophthorales

Secretome of fungus-infected aphids documents high pathogen activity and weak host response

Evolutionary relationships among basal fungi (Chytridiomycota and Zygomycota): Insights from molecular phylogenetics

Contact Info

Product

Resources

About