Relationships between sleep quality, depressive symptoms and MCI diagnosis: A path analysis

McKinnon, Anna; Beath, Alissa; Naismith, Sharon L.

doi:10.1016/j.jad.2019.05.045

Cited by 18 publications

(10 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, as a common comorbidity of depression, though exclusive studies on the anxiety of elderly adults are scarce, anxiety alone is another deleterious psychological burden for elderly adults and is more common in female elderly ( 16 ). There is a body of studies stressing external risk factors such as a pandemic that can elicit depression or anxiety, whilst few have done into the concurrence of sleep disturbance, depression, and anxiety, especially in the aged population, even sleep disturbance is strongly correlated to psychopathologies ( 17 ). Moreover, previous studies mainly emphasized the unidimensional causal relationship that treatment of depression or anxiety demonstrated an alleviation in sleep quality ( 18 ) while ignored that sleep quality improvement can espouse the rehabilitation of depression and anxiety.…”

Section: Introductionmentioning

confidence: 99%

Seeking bridge symptoms of anxiety, depression, and sleep disturbance among the elderly during the lockdown of the COVID-19 pandemic—A network approach

Zhang

Tao²,

Hou³

et al. 2022

Front. Psychiatry

View full text Add to dashboard Cite

BackgroundBesides physical changes, elderly adults are prone to have mental disorders such as anxiety, depression, and sleep disturbance, and the pandemic of COVID-19 worsened the situation. However, internal relationships and co-occurrence of psychopathologies were scarcely examined. Therefore, in the current study, through network analysis, we inspected relationships among symptoms of depression, anxiety, and sleep disturbance and identified key symptoms that espoused the disease.MethodsWe asked 1,302 elderly adults to fill in Patient Health Questionnaire-2 (depressive symptoms), the Generalized Anxiety Disorder-2 (anxiety symptoms), and the Youth Self-rating Insomnia Scale (sleep disturbance) and then constructed three networks for elderly adults, male elderly, and female elderly. Via network analysis, we accomplished four goals. First, we identified symptom with the highest centrality (i.e., strength) index for each network; then, we found the strongest correlation (i.e., edges) in each network; thirdly, we confirmed specific nodes that could bridge anxiety, depression, and sleep disturbance; the last was to compare networks based on genders. Network stability and accuracy tests were performed.ResultsNetworks of elderly adults, male elderly, and female elderly were stable, accurate, and intelligible. Among all networks, “Nervousness”- “Excessive worry” (GAD-1- GAD-2) had the strongest correlation, and “Nervousness” (GAD-1) had the highest strength and bridge strength value. When we made a comparison between female elderly's and male elderly's networks, except for the significant difference in the mean value of “Difficulty initiating sleep” (YSIS-3), the findings showed that the two networks were similar. Network stability and accuracy proved to be reliable.ConclusionsIn networks of anxiety, depression, and sleep disturbance, anxiety played a conspicuous role in comorbidity, which could be a target for practical intervention and prevention.

show abstract

Section: Introductionmentioning

confidence: 99%

Seeking bridge symptoms of anxiety, depression, and sleep disturbance among the elderly during the lockdown of the COVID-19 pandemic—A network approach

Zhang

Tao²,

Hou³

et al. 2022

Front. Psychiatry

View full text Add to dashboard Cite

show abstract

“…The Nuzum et al study also confirmed that this effect was strongly associated with quality of life (r = −0.38, p < 0.01) (32). As confirmed by large-scale longitudinal studies, both depressed mood and poor quality of life can disrupt the normal lives of older adults with mild cognitive impairment and may further contribute to their cognitive decline (33)(34)(35).…”

Section: Discussionmentioning

confidence: 71%

The Effect of Chinese Square Dance Exercise on Cognitive Function in Older Women With Mild Cognitive Impairment: The Mediating Effect of Mood Status and Quality of Life

et al. 2021

View full text Add to dashboard Cite

The present study aimed to assess the effects of square dance exercise on the cognitive function and quality of life in older women with mild cognitive impairment and to investigate the mediating role of a depressed mood and reduced quality of life in the relationship between square dance exercise and cognition. The study design was a single-blind whole-group controlled trial. A total of 136 eligible participants were divided according to their nursing home into either an experimental or control group. The nursing home grouping was determined by the drawing of lots. The Montreal Cognitive Assessment (MoCA), Quality of Life (SF-12) and Geriatric Depression Scale (GDS-15) were used to assess participants at baseline, week 9, and week 18, respectively. Generalized estimating equations (GEE) were used to compare the results at baseline with mid-test and post-test changes in cognitive function and quality of life. Maximum likelihood estimation (ML) and robust standard errors were used to perform the mediation model. The study results indicated that the experimental group (compared to the control group) had a significant improvement in cognitive function, quality of life, and mood state at baseline in the mid-test and post-test results. The results of this 18-week experiment showed that the exercise–cognition relationship was significantly mediated by a reduction in depressive symptoms (indirect effect: β = −0.375; 95% CI = −0.864 to −0.069) and an improvement in quality of life (indirect effect: β = −0.678; 95% CI = −1.222 to −0.290). This study revealed the effects of moderate-intensity square dance exercise on cognitive function and quality of life in older Chinese women with mild cognitive impairment and explored the potential mediating mechanisms. These findings can be used to inform the development of public health policies to promote brain health in older adults with mild cognitive impairment.

show abstract

“…Moreover, several types of sleep disturbances have been shown to affect cognitive functioning. Some longitudinal studies found that insomnia is a risk factor for mild cognitive impairment and dementia [13,21,35]. In patients with multiple sclerosis, sleep disorders have been shown to impair cognitive functioning, especially in executive functioning [36].…”

Section: Discussionmentioning

confidence: 99%

Sleep Disturbance Severity is Associated With Cognitive Impairment in Patients With First-episode, Treatment-naïve Major Depressive Disorders

Cui

Liu

et al. 2020

Preprint

View full text Add to dashboard Cite

BackgroundSleep disorders and cognitive impairment are common in patients with major depressive disorder (MDD), though the relationship between the two remains unclear. We investigated this association in first-episode, treatment-naïve patients with MDD.MethodWe analyzed data from 242 patients withMDD. We divided the patients into 2 groups based on sleep disturbance severity and compared the cognitive impairment odds ratios in different domains between the groups.ResultsA total of 121 pairs of patients were matched (age39.4±10.1, 70.2% female). After propensity score matching, the odds ratios for cognitive impairment in patients with MDD and serious sleep disorders were 1.922 (1.068–3.459, P= 0.029) in executive functioning; 2.023 (1.211–3.379, P= 0.007) in executive shifting; 1.749 (1.000–3.060, P = 0.050) in executive inhibition; and 1.813 (1.038–3.167, P = 0.037) in information processing speed.LimitationsThe cross-sectional data on the relationship between sleep disorders and cognitive impairment were weak. Our study population was restricted to Chinese adults aged 18 to 65 years, so the results may not be generalizable to other populations.Because our sample size was limited, some variables were not included in the study.ConclusionsSleep disturbance is associated with cognitive impairment in the domains of executive functioning and information processing speed in first-episode, treatment-naïve patients with MDD. Sleep problems can be important symptoms for physicians in clinical practice and can aid in recognizing cognitive impairment in patients with MDD. Further study is required to confirm our results.Trial registrationClinicalTrials.gov: NCT02023567; registration date: December 2013.

show abstract

Relationships between sleep quality, depressive symptoms and MCI diagnosis: A path analysis

Cited by 18 publications

References 49 publications

Seeking bridge symptoms of anxiety, depression, and sleep disturbance among the elderly during the lockdown of the COVID-19 pandemic—A network approach

Seeking bridge symptoms of anxiety, depression, and sleep disturbance among the elderly during the lockdown of the COVID-19 pandemic—A network approach

The Effect of Chinese Square Dance Exercise on Cognitive Function in Older Women With Mild Cognitive Impairment: The Mediating Effect of Mood Status and Quality of Life

Sleep Disturbance Severity is Associated With Cognitive Impairment in Patients With First-episode, Treatment-naïve Major Depressive Disorders

Contact Info

Product

Resources

About