Relationships Between Intravaginal Ejaculatory Latency Time and National Institutes of Health-Chronic Prostatitis Symptom Index in the Four Types of Premature Ejaculation Syndromes: A Large Observational Study in China

Abstract

Introduction Besides lifelong premature ejaculation (LPE) and acquired premature ejaculation (APE), Waldinger and Schweitzer proposed two addition PE syndromes (variable PE [VPE] and subjective PE [SPE]). Aim We assessed the associations between intravaginal ejaculatory latency time (IELT) and National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) in men with different PE syndromes. Methods From September 2011 to September 2012, a total of 4,000 men were enrolled from the Anhui province of China. Subjects were required to complete a verbal questionnaire, including demographic information, medical and sexual history (e.g., IELT), and self-estimated scales (e.g., NIH-CPSI). Main Outcome Measures IELT; NIH-CPSI; the new classification of PE syndromes. Results Of 3,016 of the men evaluated, 25.80% complained of PE. Distribution of the four PE syndromes among men with complaints of PE was as follows: LPE, 12.34%; APE, 18.77%; VPE, 44.09%; and SPE, 24.81%. Men with complaints of PE reported worse NIH-CPSI scores and lower IELT than men without complaints of PE (P < 0.001 for all). Moreover, total and subdomain scores of NIH-CPSI were higher in men with APE, and IELT was higher in men with SPE. IELT was negatively associated with NIH-CPSI scores in men with complaints of PE. Negative relationships between total and subdomain scores of NIH-CPSI and IELT were stronger in men with APE (total scores: adjusted r = −0.68, P < 0.001; pain symptoms: adjusted r = −0.70, P < 0.001; urinary symptoms: adjusted r = −0.67, P < 0.001; quality of life impact: adjusted r = −0.64, P < 0.001). Conclusion Men with complaints of PE reported worse NIH-CPSI scores than men without complaints of PE. Relationships between IELT and NIH-CPSI scores were strongest in men with APE.

Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta-Analysis

“… Trial flow diagram. *The E l‐ S akka et al., 2008 study (reference [31]) is included in both samples; references [38] and [39] refer to the same study. ED = erectile dysfunction, P E = premature ejaculation; IIEF = I nternational I ndex of E rectile F unction.…”

The pathophysiology of acquired premature ejaculation

“…This syndrome includes urogenital pain, ejaculatory pain, urinary dysfunction, and sexual dysfunction. In the literature, CP has been closely linked with PE (42,117-120). While the co-existence of these conditions is common, a true causal relationship or mechanism has not been established.…”

Psycho-social factors associated with premature ejaculation among the patients attending in a tertiary level psychiatric hospital, Dhaka, Bangladesh

“…In this study, the PE cases included (confirmed and probable cases of PE) based on a Premature Ejaculation and Diagnostic Tool (PEDT) score of > 9 and proportion of premature ejaculation was found 26.4% (74 out of 280 men), which was consistent with previously reported majority of the study findings. [7][8][9][10][11][12] Due to the unavailability of published data on premature ejaculation in Bangladesh, results could not be compared in Bangladesh context. In Malaysia, studies have reported prevalence of PE of 29.0% and 49.1%.…”

“…On average, most studies reported a prevalence ranging from 20 % to 31.6%. [7][8][9][10][11][12] The Diagnostic and Statistical Manual of Mental Disorders (DSM), edition-IV (Text Revision) by the American Psychiatric Association (APA) defines PE as persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the person wishes it, with the disturbance causing marked distress or interpersonal difficulty and is not due exclusively to the direct effects of a substance (e.g., withdrawal from opioids). 6 PE is classified into four groups, namely, lifelong PE, acquired PE, natural variable PE and premature-like ejaculatory dysfunction.…”