2011
DOI: 10.1186/1476-069x-10-6
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Relationships between heavy metal concentrations in three different body fluids and male reproductive parameters: a pilot study

Abstract: BackgroundAnimal studies have shown the reproductive toxicity of a number of heavy metals. Very few human observational studies have analyzed the relationship between male reproductive function and heavy metal concentrations in diverse biological fluids.MethodsThe current study assessed the associations between seminal and hormonal parameters and the concentration of the 3 most frequent heavy metal toxicants (lead, cadmium and mercury) in three different body fluids. Sixty one men attending infertility clinics… Show more

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Cited by 146 publications
(93 citation statements)
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“…All of these studies have been adjusted for the infl uence of age and current smoking (66,(105)(106)(107)(108)(109), and for other metals (66,105,(107)(108)(109). Other studies (110)(111)(112)(113)(114) have not found any association between low-level lead exposure and semen quality or endocrine function in men.…”
Section: Effects Of Environmental Exposure To Metals On Reproductive mentioning
confidence: 99%
“…All of these studies have been adjusted for the infl uence of age and current smoking (66,(105)(106)(107)(108)(109), and for other metals (66,105,(107)(108)(109). Other studies (110)(111)(112)(113)(114) have not found any association between low-level lead exposure and semen quality or endocrine function in men.…”
Section: Effects Of Environmental Exposure To Metals On Reproductive mentioning
confidence: 99%
“…Hernandez-Ochoa et al (9) found that low lead concentrations in seminal fluid (0.2 µg/dL) were associated with impaired semen quality, motility, morphology, and sperm concentration. In contrast, Mendiola et al (10) found a relationship between levels of lead in seminal fluid and low motility, but found that measured lead concentrations of 9.75 µg/dL in blood and 2.78 µg/dL in blood plasma had no significant effect on morphology, motility, or sperm concentration. Meeker et al (11) measured a lead concentration of 1.5 µg/dL in blood and reported no effect on sperm concentration or motility.…”
Section: Introductionmentioning
confidence: 89%
“…[ [43][44][45] Kadmiyumun erkek üreme sistemi üzerine etkilerinin incelendiği insan çalışmaları sonucunda, özetle; testiküler nekroz ile serum testosteron düzeyinde ve sperm sayısın-da azalma olduğu, serum kadmiyum seviyesi 1,5 μg/L'den daha fazla olan erkek bireylerde, oluşan her ejakülatta, sperm sayısında, hareketliliğinde ve yoğunluğunda azalma, olgunlaşmamış sperm şekli ve anomalili sperm oranında artma gözlendiği belirtilmektedir.…”
Section: [42]unclassified