Relationships between gene transcription and contaminant concentrations in Baltic ringed seals: A comparison between tissue matrices

Characterizing the marine mammal exposome by iceberg modeling, linking chemical analysis and in vitro bioassays

“…5,11,13,14 Already young marine mammals possess a high chemical burden, as lipophilic chemicals are transferred from mother to their offspring during pregnancy and lactation. 11,[15][16][17][18][19] HOCs have a negative impact on the health and survival of marine mammals, 11,20,21 and can cause, amongst others, immunodecient effects, [22][23][24][25] reproduction dysfunction, [26][27][28] and endocrine disruption. 3,[29][30][31] The production and use of some HOCs are regulated; they have partly been banned almost two decades ago to prevent adverse environmental and health effects, e.g.…”