Relationships between epistaxis, migraines, and triggers in hereditary hemorrhagic telangiectasia

Abstract

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Embolisation of PAVMs reported to improve nosebleeds by a subgroup of patients with hereditary haemorrhagic telangiectasia

“…By 6 months, compensatory polycythaemia [3] and higher cardiac outputs [9] have also reversed, and this is a useful time-point to assess sustained clinical responses to embolisation. A standard “Have you noticed any difference?” question is asked, intended to capture respiratory [2, 3] and neurological [4, 6, 10] symptoms. Surprisingly, both spontaneously and in response to this question, patients frequently reported that their nosebleeds had improved following this apparently unconnected treatment.…”

“…The NRES Committee East Midlands-Derby 1 Research Ethics Committee approved the study and online launch at https://www1.imperial.ac.uk/nhli/cardio/vascular/pulmonary_vascular/hht_pavms/hhtsurvey/ The basic study design has been reported previously [10]. Briefly, online informed consent was obtained from all participants who were then asked to provide details on general aspects of their HHT phenotype, before proceeding to a series of questions regarding nosebleed responses to assessments and interventions.…”

Hereditary hemorrhagic teleangiectasia: the topical problems of diagnostics and surgical treatment

“…У пациентов с носовыми кровотечениями часто развивается железодефицит ная анемия [22]. Обследование пациентов с НГТ по казало, что 70% из них нуждаются в восполнении дефицита железа, а 20% из них проводили, по край ней мере, 10 переливаний крови [23].…”

Dietary supplement use and nosebleeds in hereditary haemorrhagic telangiectasia ‒ an observational study

“…HHT nosebleeds are highly variable, and generally difficult to predict. However, in recent studies by our group, HHT patients reported that nosebleeds could be precipitated by certain food groups (13,14). Spontaneously volunteered precipitant foods included red wine, spices, chocolate, coffee, berries, oily fish, and other food items that contain high levels of naturally occurring salicylates and other anti-platelet agents (13).…”