Relationships between dietary intake and cognitive function level in Korean elderly people

Lee, L; Kang, Suh-Jung; Lee, H O; Lee, B H; Park, J S; Kim, J H; Jung, In-Kyung; Park, Y J; Lee, J E

doi:10.1038/sj.ph.1900729

Cited by 72 publications

(55 citation statements)

References 23 publications

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“…Previous cross-sectional studies showed inconsistent findings for MUFA and (saturated) fat intake, but a positive association between dietary cholesterol and cognitive impairment. [14][15][16][17] Prospective data from the Zutphen Elderly Study showed that moderate fish consumption was associated with a decreased risk of cognitive decline. 13 Recently, a few prospective population-based studies have examined this issue in relation to dementia.…”

Section: Resultsmentioning

confidence: 98%

“…Population-based studies on dietary fat intake and cognitive function are scarce, especially among the middle aged. [13][14][15][16][17] Here, we examined the relationship between dietary intake of fatty acids and multiple cognitive domains in a cross-sectional populationbased study among middle-aged men and women living in the Netherlands.Materials and methods. Study population.…”

mentioning

confidence: 99%

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Dietary intake of fatty acids and fish in relation to cognitive performance at middle age

Kalmijn¹,

Boxtel²,

Ocké³

et al. 2004

Neurology

439

263

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Section: Resultsmentioning

confidence: 98%

mentioning

confidence: 99%

Dietary intake of fatty acids and fish in relation to cognitive performance at middle age

Kalmijn¹,

Boxtel²,

Ocké³

et al. 2004

Neurology

439

263

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“…The effects of mt-nutrient deficiency and supplementation on cognitive dysfunction, AD, and PD Significantly lower dietary intake of vegetables, fruits, vitamin A, thiamin, riboflavin, and niacin has been associated with lower scores of cognitive function (Lee et al 2001). Also, higher intake of vitamins E, A, B6, and B12 has been related to better performance on visuospatial recall and/or abstraction tests (La Rue et al 1997).…”

Section: Mt-nutrients and Mitochondrial Decaymentioning

confidence: 97%

Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease

Liu¹,

Ames²

2005

Nutritional Neuroscience

127

116

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Mitochondrial decay due to oxidative damage is a contributor to brain aging and age-related neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). One type of mitochondrial decay is oxidative modification of key mitochondrial enzymes. Enzyme dysfunction, that is due to poor binding of substrates and coenzymes may be ameliorated by supplementing adequate levels of substrates or coenzyme precursors. Such supplementation with mitochondrial nutrients (mt-nutrients) may be useful to prevent or delay mitochondrial decay, thus prevent or treat AD and PD. In the present review, we survey the literature to identify mt-nutrients that can (1) protect mitochondrial enzymes and/or stimulate enzyme activity by elevating levels of substrates and cofactors; (2) induce phase-2 enzymes to enhance antioxidant defenses; (3) scavenge free radicals and prevent oxidant production in mitochondria, and (4) repair mitochondrial membrane. Then, we discuss the relationships among mt-nutrient deficiency, mitochondrial decay, and cognitive dysfunction, and summarize available evidence suggesting an effect of mt-nutrient supplementation on AD and PD. It appears that greater effects might be obtained by longer-term administration of combinations of mt-nutrients. Thus, optimal doses of combinations of mt-nutrients to delay and repair mitochondrial decay could be a strategy for preventing and treating cognitive dysfunction, including AD and PD.

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“…Moreover, secondary plant metabolite-rich extracts prepared from non-nutritional plants have also been found to prevent aging-related increase in oxidative stress and to improve the cognitive performance in aged animals [126,127]. Furthermore, in women aged 60 years and above, Lee et al [128] observed that subjects of poor cognitive performance in the Mini-Mental State Examination had significantly lower intakes of vegetables, fruits and spices that those of the normal score group. Based on data from the Nurses' Health Study, more than 15,000 women were recruited by Kang et al [129] for a prospective assessment of fruit and vegetable intake in relation to cognitive function.…”

Section: In Vivo Effect Of Dietary Plant Foods On Brain Agingmentioning

confidence: 95%

Plant Foods and Brain Aging: A Critical Appraisal

Schaffer

Eckert²,

S³

et al. 2006

Local Mediterranean Food Plants and Nutraceuticals

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In the 21st century, human aging will be one of the biggest challenges for most societies throughout the world. The decline in human fitness is a typical hallmark of the aging process. Aside from the cardiovascular system, the brain most often suffers significantly from the life-long impact of stressors, such as reactive oxygen and nitrogen species. Oxytosis, i.e. oxidative stress-induced cell death, has been identified to play a major role in the development and onset of chronic diseases. Foods, especially of plant origin, are rich in antioxidants and numerous in vivo data suggest that a diet rich in fruits and vegetables supports the maintenance of animal and human health. These beneficial effects also extend to the central nervous system, which, due to the presence of the blood-brain barrier, tightly controls the influx of metabolites and nutrients. In earlier studies the impact of antioxidant vitamins, such as alpha-tocopherol and ascorbic acid, on brain health has been of interest. Recently, the focus moved to assessing the potential of unsaturated fatty acids and secondary plant metabolites, particularly of polyphenols, to act as neuroprotectants. Considerable experimental evidence suggests that polyphenols and other plant-derived bioactivities affect animal and human brain function not only by directly lowering oxidative stress load but also by modulating various signal transduction pathways.

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Relationships between dietary intake and cognitive function level in Korean elderly people

Cited by 72 publications

References 23 publications

Dietary intake of fatty acids and fish in relation to cognitive performance at middle age

Dietary intake of fatty acids and fish in relation to cognitive performance at middle age

Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease

Plant Foods and Brain Aging: A Critical Appraisal

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