Relationships Among Subgross Anatomy, Computed Tomography, and Histologic Findings in Dogs With Disease Localized to the Pulmonary Acini

Scrivani, Peter V.; Thompson, Margret S.; Dykes, Nathan L.; Holmes, Nedra L.; Southard, Teresa; Gerdin, Jodie A.; Bezuidenhout, Abraham J.

doi:10.1111/j.1740-8261.2011.01881.x

Cited by 18 publications

(22 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dogs are similar to cats and also lack secondary pulmonary lobules, and the pulmonary acinus has been suggested to be the important highresolution CT (HRCT) unit of the canine lung. 26 The acinus is defined as the region of the lung supplied by a single terminal bronchiole, representing the smallest functional unit of the lung. Because it is smaller than the secondary pulmonary lobule that is the smallest visible structure on HRCT, we believe that the pulmonary acinus is not a replaceable term as the important HRCT unit of the feline (or canine) lung.…”

Section: Lack Of a Secondary Pulmonary Lobule In Cats And Implicatimentioning

confidence: 99%

Perspectives in veterinary medicine: Description and classification of bronchiolar disorders in cats

Reinero

Masseau

Grobman

et al. 2019

Veterinary Internal Medicne

View full text Add to dashboard Cite

This Perspectives in Veterinary Medicine article seeks to define, describe putative causes, and discuss key diagnostic tests for primary and secondary bronchiolar disorders to propose a classification scheme in cats with support from a literature review and case examples. The small airways (bronchioles with inner diameters <2 mm), located at the transitional zone between larger conducting airways and the pulmonary acinus, have been overlooked as major contributors to clinical syndromes of respiratory disease in cats. Because the trigger for many bronchiolar disorders is environmental and humans live in a shared environment with similar susceptibility, understanding these diseases in pet cats has relevance to One Health. Thoracic radiography, the major imaging modality used in the diagnostic evaluation of respiratory disease in cats, has low utility in detection of bronchiolar disease. Computed tomography (CT) with paired inspiratory and expiratory scans can detect pathology centered on small airways. In humans, treatment of bronchiolar disorders is not well established because of heterogeneous presentations and often late definitive diagnosis. A review of the human and veterinary medical literature will serve as the basis for a proposed classification scheme in cats. A case series of cats with CT or histopathologic evidence of bronchiolar lesions or both, either as a primary disorder or secondary to extension from large airway disease or interstitial lung disease, will be presented. Future multi‐institutional and multidisciplinary discussions among clinicians, radiologists, and pathologists will help refine and develop this classification scheme to promote early and specific recognition and optimize treatment.

show abstract

Section: Lack Of a Secondary Pulmonary Lobule In Cats And Implicatimentioning

confidence: 99%

Perspectives in veterinary medicine: Description and classification of bronchiolar disorders in cats

Reinero

Masseau

Grobman

et al. 2019

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…Computed tomography (CT) is a sensitive diagnostic tool to localize lung lesions because of its high spatial resolution without superimposition. Because it provides information on airway structure and lung parenchyma, CT use to investigate respiratory symptoms has been increasing in veterinary medicine .…”

Section: Introductionmentioning

confidence: 99%

Bronchoalveolar lavage affects computed tomographic and radiographic characteristics of the lungs in healthy dogs

Lim

Sung

Min

et al. 2018

Vet Radiology Ultrasound

View full text Add to dashboard Cite

Bronchoalveolar lavage is a common diagnostic test for dogs with suspected pulmonary disease, however there is no published information on whether this procedure could affect the imaging characteristics of the lungs. Aims of this prospective experimental study were to describe computed tomography (CT) and radiographic features of the lungs after bronchoalveolar lavage in a sample of healthy dogs. Thoracic CT and radiographic images of eight healthy Beagles were acquired at the following time points: before bronchoalveolar lavage, immediately following bronchoalveolar lavage, and at 2, 4, 8, 12, and 24 h following bronchoalveolar lavage. Lung consolidation or interstitial patterns were seen in CT and radiographic images immediately after the procedure. Radiographic lung patterns resolved within 2 h and CT patterns resolved within 24 h. Resolution of the CT pulmonary patterns in the ventral areas of the lungs was delayed compared to the dorsal areas. Mean CT imaging scores differed over time (P < 0.001), while mean radiographic imaging scores did not differ over time. This study suggests that thoracic radiography and CT imaging assessments should precede bronchoalveolar lavage procedures if possible, or be performed at least 24 h afterward.

show abstract

“…We could observe how solid consolidations on D0 scans had transformed into GGO three days later. This change from airspace consolidation to ground-glass opacity has been reported in sequential thoracic radiographs in people with LPHS (Im and others 1989) and may reflect degrees of airspace filling (Scrivani and others 2012). Solid nodules and ground-glass nodules were found in 8/10 and 10/10 dogs on their initial scan, respectively.…”

Section: Discussionmentioning

confidence: 56%

Serial CT features of pulmonary leptospirosis in 10 dogs

et al. 2014

View full text Add to dashboard Cite

Leptospirosis pulmonary haemorrhage syndrome (LPHS) is a frequent manifestation of Leptospira infection in dogs and is associated with a high morbidity and mortality. Three helical 16-slice thoracic CT scans were performed in 10 dogs naturally infected with Leptospira, within 24 hours of admission, and three and seven days later. Patients were sedated and scanned without breathhold, with a protocol adapted for rapid scanning. One dog died of respiratory failure on the morning following the first scan. On the initial scan, imaging features of LPHS included ground-glass nodules (10/10), peribronchovascular interstitial thickening (10/10), diffuse or patchy ground-glass opacity (9/10), solid nodules (8/10) and consolidation (7/10). Temporary bronchiolar dilation was observed in all dogs in association with peribronchovascular interstitial thickening, which had completely resolved at day 7. Nodules were with few exceptions assigned to the centrilobular region. Regression of lesion severity was observed after each subsequent scan. Consolidation and solid nodules changed over time into lesions of ground-glass attenuation. Pleural effusion (3/10) and mediastinal effusion (2/10) were mild and transient. Lesion severity appeared unassociated with survival to discharge.

show abstract

Relationships Among Subgross Anatomy, Computed Tomography, and Histologic Findings in Dogs With Disease Localized to the Pulmonary Acini

Cited by 18 publications

References 35 publications

Perspectives in veterinary medicine: Description and classification of bronchiolar disorders in cats

Perspectives in veterinary medicine: Description and classification of bronchiolar disorders in cats

Bronchoalveolar lavage affects computed tomographic and radiographic characteristics of the lungs in healthy dogs

Serial CT features of pulmonary leptospirosis in 10 dogs

Contact Info

Product

Resources

About