Relationships among some serum enzymes, negative energy balance parameters, parity and postparturient clinical (endo)metritis in Holstein Friesian cows – Short communication

Abstract

Activities of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase, and concentrations of serum metabolites [beta-hydroxybutyrate (BHB) and non-esterified fatty acids (NEFA)] of primiparous (n = 83) and multiparous (n = 213) Holstein cows were studied as possible predictors of retained fetal membranes (RFM), grade 2 clinical metritis (CM) and clinical endometritis (CEM). A logistic regression model was used to calculate odds ratios (OR) for the prevalence of CM diagnosed between 0–5, 6–10 and 11–20 days in milk (DIM) and for the prevalence of CEM diagnosed between 22–28 and 42–49 DIM. The activities of the examined serum enzymes did not show significant associations either with CM or with CEM. For NEFA sampled on days 0 and 5, an OR of 2.38 for CM 0–20 DIM and an OR of 2.58 for CM 11–20 DIM was found. For BHB sampled on days 0 and 5, an OR of 8.20 for CEM 22–28 and 42–49 DIM and an OR of 1.98 for CM 6–10 DIM were found. The prevalence of RFM was higher in ≥ 4 parity cows compared to primiparous cows (46.3% vs. 26.5%). BHB and NEFA levels measured between 0 and 5 DIM could have a predictive ability for postpartum uterine disorders such as RFM, CM and CEM.

Ultrasonographic Screening of Dairy Cows with Normal Uterine Involution or Developing Postpartum Uterine Disease Using B‐Mode, Color, and Spectral Doppler

“…Te energy balance (EB) status afects reproductive performance, including frst postpartum ovulation, postpartum uterine involution, and uterine immune response [4][5][6][7], resulting in impaired uterine involution [8]. Te negative relationship between pronounced NEB and postpartum uterine disease (PUD) in dairy cows has been reported [9][10][11]. PUD includes clinical metritis (Met), puerperal metritis (PM), clinical endometritis (CE), subclinical endometritis (SE) [12,13], and cervicitis [14,15].…”