Relationship of weight loss to cardiovascular risk factors in morbidly obese individuals.

Abstract

Weight reduction through a multidisciplinary VLCD program significantly reduces risk factors for cardiovascular disease; for morbidly obese individuals, improvements in risk factors were significantly and linearly related to changes in the BMI.

A Systematic Review on Use of a Handheld Indirect Calorimeter to Assess Energy Needs in Adults and Children

“…Unfortunately, the obesity epidemic will only continue to increase. It is projected that by the year 2010 the percentage of obese individuals will increase 5% and normal-weight individuals will decrease 4% (2,3). Because of the growing obesity problem, effective weight-management solutions are needed.…”

An Evidenced-based Assessment of Preoperative Weight Loss in Bariatric Surgery

“…In addition to the physiologic derangements and comorbid conditions associated with obesity (i.e., type II diabetes, hypertension, sleep apnea, etc. ), the presence of excess abdominal fat also increases the technical difficulties of the operative procedure and jeopardizes the healing response thereby compromising the integrity of surgical repairs, organ function and the incisions used in modern surgery [1][2][3][4][5][6][7].…”

Benefits and risks of antiobesity agents

“…In addition, antiobesity agents facilitate long-term weight maintenance and lifestyle changes such as a lower fat intake (10), intake of more vegetables and fruit (1,2,10), and more physical activity (10); the benefits may far outweigh the potential risks. Emerging data indicate that maintenance of significant weight loss is accompanied by significant improvement in blood pressure (11), serum lipids (11), and glycemic control in diabetes (12). Maintaining even modest amounts of weight loss significantly decreases the risk of developing diabetes (13).…”

“…Maintaining even modest amounts of weight loss significantly decreases the risk of developing diabetes (13). Modest amounts of weight gain significantly increase the risk of developing coronary artery disease (14) and modest weight loss significantly reduces atherogenic risk factors (11)(12)(13). …”