Relationship of Tryptophane to the Incidence of Dental Caries

Turner, Naomi C.; Crowell, George E.

doi:10.2105/ajph.38.4.525

Cited by 4 publications

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References 5 publications

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“…72 74 5 In experimental groups of children and college students, lactobacilli have been reduced in number by the use of penicillin in dental powder twice daily.7678 Ammonia nitrogen developed naturally in the bacterial plaques has been reported to inhibit the growth of lactobacilli,79' 80 and well controlled experiments are now in progress in Illinois to test thoroughly the effectiveness of dibasic ammonium phosphate, used as a mouth rinse or a powder dentifrice, in the reduction of the counts of these aciduric bacteria in children's mouths. Recently the presence of the amino acid, tryptophane, in the salivas of patients has been reported to be associated with a reduction in the caries rate, [81][82][83] whereas the addition experimentally of indol and one other decomposition product of tryptophane to cultures of lactobacilli has been reported to destroy these bacteria.84 Two other amino acids, alanine and aspartic acid, will in immunes' salivas, readily become deaminized which is the initial step in the breakdown of an amino acid to ammonia.85 4. Carbohydrate Substrate Government reports, it has been pointed out, indicate that sugar consumption increased from 12.1 lb.…”

Section: Acidogenic Organismsmentioning

confidence: 99%

The Caries Problem of the School Child

Easlick¹

1949

Am J Public Health Nations Health

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EVERY dentist should pause long enough to ask himself the question that many others frequently ask, "What, anyhow, can dentistry contribute to a child's health?"Were each operator to ponder his answer thoroughly, unemotionally, and scientifically, he should answer: " Dentistry, (1) with family codperation, can control most children's dental caries;(2) can, with the child's codperation, prevent or control soft tissue inflammation and disease of the supporting tissues of the teeth-and even can establish a regime of home care and periodic office treatment that will prevent much of the periodontal disease of adult life; (3) can, with specialist cooperation, correct maloccluding teeth, and prevent a relatively small number of the gross tooth irregularities that may interfere with mastication, with the health of the supporting tissues, and with the emotional stability of a young person; (4) can, with specialist cooperation, treat the problems arising from anomalies of the oral cavity-the cleft palate, congenitally missing teeth, supernumerary teeth, hypoplastic teeth, and other developmental dental abnormalities; (5) can treat and restore young teeth involved in accidents; (6) can detect oral cancer in the early stages; (7) can prevent and eliminate oral infection which may contribute to body disease."

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Section: Acidogenic Organismsmentioning

confidence: 99%