Relationship of sitting time and physical activity with non-alcoholic fatty liver disease

Ryu, Seungho; Chang, Yoosoo; Jung, Hyun Suk; Yun, Kyung Eun; Kwon, Min‐Jung; Choi, Yuni; Kim, Chan-Won; Cho, Juhee; Suh, Byung-Seong; Cho, Yong Kyun; Chung, Eun Chul; Shin, Hocheol; Kim, Yeon Soo

doi:10.1016/j.jhep.2015.07.010

Cited by 162 publications

(189 citation statements)

References 57 publications

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“…They showed an association between habitual physical activity and intrahepatic fat content [77]. Furthermore, a large cross sectional study by Ryu (2015) fully supports this statement, that prolonged sitting times are positively associated with the prevalence of NAFLD [42]. Therefore, supporting patients to achieve and sustain regular activity is a key issue in NAFLD management [12].…”

Section: The Importance Of Regular Supportmentioning

confidence: 87%

Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study (Preprint)

Pfirrmann¹,

Huber²,

Schattenberg³

et al. 2018

Preprint

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Section: The Importance Of Regular Supportmentioning

confidence: 87%

Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study (Preprint)

Pfirrmann¹,

Huber²,

Schattenberg³

et al. 2018

Preprint

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“…20 Data on demographic characteristics, medication use, medical history, education level, smoking and alcohol intake were also collected by standardized, self-administered questionnaires as previously described. 18, 19 Physical activity levels and sitting time were assessed using the validated Korean version of the International Physical Activity Questionnaire Short Form (IPAQ-SF). 21, 22 Physical activity levels were classified into 3 categories: inactive, minimally active (600 MET-minutes per week), and health-enhancing physically active (HEPA; 3,000 MET-minutes per week) as previously described.…”

Section: Editorial P 783mentioning

confidence: 99%

“…21, 22 Physical activity levels were classified into 3 categories: inactive, minimally active (600 MET-minutes per week), and health-enhancing physically active (HEPA; 3,000 MET-minutes per week) as previously described. 19 Usual dietary intake was assessed using a 103-item, self-administered food frequency questionnaire (FFQ) designed and validated for use in Korea. 23 The validity and reproducibility of our FFQ were evaluated previously by comparing nutrient and food intake derived from 12 24-h dietary recalls during 4 seasons and with a second FFQ administered 1 year later.…”

Section: Editorial P 783mentioning

confidence: 99%

“…18, 19 The cohort used in this study consisted of 85,691 men and women, aged 18 years or older, who were evaluated with echocardiography as part of a comprehensive health examination between March 2011 and December 2014.…”

Section: Study Populationmentioning

confidence: 99%

“…18, 19 Serum GGT levels were measured enzymatically using an automatic analyzer (Modular D2400; Roche Diagnostics, Tokyo, Japan). Both low-and high-level quality control (QC) materials were used, with coefficients of variation (CV) of 1.57-5.45% and 0.76-4.45%, respectively.…”

Section: Measurementsmentioning

confidence: 99%

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Relationship Between γ-Glutamyltransferase Levels and Left Ventricular Diastolic Dysfunction

Ryu

Chang

Kang

et al. 2017

Circ J

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tions with many cardiovascular disease (CVD) risk factors, as well as future risks of diabetes, chronic kidney disease, coronary artery disease (CAD), HF, stroke, and CVD mortality. 12-16 Therefore, it can be hypothesized that high levels of serum GGT may play a potential role in the development of subclinical LV diastolic dysfunction and LVH. Studies of subclinical HF can provide valuable information on clinical HF outcomes, particularly regarding the early stages of HF free from confounding secondary processes such as chronic liver damage. Only one study found that serum GGT predicted LV dilation and dysfunction in 40 patients with acute myocardial infarction. 17 To date, the relationship between serum GGT levels and LV function has not been studied using large cohorts of healthy adults. Heart failure (HF) is a major public health problem associated with high morbidity, mortality and healthcare expenditure. 1-3 Previous studies have demonstrated that subclinical left ventricular (LV) diastolic dysfunction and LV hypertrophy (LVH) predict the development of clinical HF. 4-6 Furthermore, LV diastolic dysfunction is associated with increased risk of sudden death, and the presence of LVH is a strong independent risk factor for future cardiac events and all-cause mortality. 7,8 Because of the serious consequences of overt HF, there is substantial interest in developing strategies and identifying potential risk factors to prevent or reduce the progression of LV dysfunction and hypertrophy.Serum γ -glutamyltransferase (GGT) has been widely used as an index of alcohol intake and liver dysfunction. 9,10 Recently, serum GGT was proposed as a sensitive marker of oxidative stress, 11 because it has dose-response associa- Editorial p 783Received October 26, 2016; revised manuscript received January 10, 2017; accepted January 23, 2017; released online Background: The goal of this study was to examine the association of serum γ -glutamyltransferase (GGT) levels with left ventricular (LV) diastolic dysfunction and LV hypertrophy.

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The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health

2016

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Relationship of sitting time and physical activity with non-alcoholic fatty liver disease

Cited by 162 publications

References 57 publications

Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study (Preprint)

Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study (Preprint)

Relationship Between γ-Glutamyltransferase Levels and Left Ventricular Diastolic Dysfunction

The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health

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