Relationship of Quadriceps Muscle Thickness with Motor Paralysis and Muscle Echo Intensity in Post-Stroke Patients

Maeda, Hisashi; Imada, Ken; Ishida, Kōji; Akima, Hiroshi

doi:10.1159/000500415

Cited by 12 publications

(8 citation statements)

References 48 publications

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“…In the stepwise regression analysis, MT of the QF was extracted to predict EI of the QF in both Japanese and Brazilian participants. The same relationship was found in a simple regression analysis in the present study (Table 4), and similar findings were demonstrated in previous studies on older individuals [5,28] and stroke patients [30]. In support of this relationship, the EIs were significantly correlated with LBM in both Japanese and Brazilian participants, suggesting that muscle size is a strong predictor of EI in older individuals.…”

Section: Plos Onesupporting

confidence: 93%

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Comparison of muscle quality and functional capacity between Japanese and Brazilian older individuals

Akima¹,

Yoshiko²,

Radaelli³

et al. 2020

PLoS ONE

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Muscle quality is well-known to decrease with aging and is a risk factor for metabolic abnormalities. However, there is a lack of information on race-associated differences in muscle quality and other neuromuscular features related to functional performance. This study aimed to compare muscle quality, function, and morphological characteristics in Japanese and Brazilian older individuals. Eighty-four participants aged 65–87 years were enrolled in the study (42 Japanese: 23 men, 19 women, mean age 70.4 years; 42 Brazilians: 23 men, 19 women, mean age 70.8 years). Echo intensity (EI) and muscle thickness (MT) of the quadriceps femoris were measured using B-mode ultrasonography. A stepwise multiple linear regression analysis with EI as a dependent variable revealed that MT was a significant variable for Japanese participants (R2 = 0.424, P = 0.001), while MT and subcutaneous adipose tissue (SCAT) thickness were significant variables for Brazilian participants (R2 = 0.490, P = 0.001). A second stepwise multiple linear regression analysis was performed after excluding MT and SCAT thickness from the independent variables. Sex and age for Japanese participants (R2 = 0.381, P = 0.001) and lean body mass and body mass index for Brazilian participants (R2 = 0.385, P = 0.001) were identified as significant independent variables. The present results suggest that MT is closely correlated with muscle quality in Japanese and Brazilian older individuals. Increases in muscle size may induce decreases in intramuscular adipose tissue and/or connective tissues, which are beneficial for reducing the risks of metabolic impairments in Japanese and Brazilian older individuals.

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Section: Plos Onesupporting

confidence: 93%

“…The EIs of the RF, VL, and QF in the present study were inversely correlated with the MTs (Table 3), consistent with some previous studies [5,29,30]. Fukumoto et al [28] also reported that EI of the QF was negatively correlated with MT of the QF (r = -0.33, P < 0.01).…”

Section: Plos Onesupporting

confidence: 92%

Comparison of muscle quality and functional capacity between Japanese and Brazilian older individuals

Akima¹,

Yoshiko²,

Radaelli³

et al. 2020

PLoS ONE

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“…Previous studies have reported that there is a significant negative association between MT and EI on quadriceps femoris in healthy older adults 19,29 ) . A previous study of acute stroke patients by Maeda et al reported a significant negative association between MT and EI of the quadriceps femoris 30) . These previous findings suggest that quantitative and qualitative changes of individual muscles are associated with each other.…”

Section: Discussionmentioning

confidence: 82%

Differences in muscle thickness and echo intensity between stroke survivors and age- and sex-matched healthy older adults

et al. 2020

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The stroke survivors exhibit change in muscle quantity and quality compared to healthy older adults. This study aimed to compare the muscle thickness (MT) and echo intensity (EI) values of individual muscles between stroke survivors and age-and sex-matched healthy older adults. Methods : In total, 27 stroke survivors and 34 healthy older adults participated in this study. The MT and EI values of the following muscles were assessed from transverse ultrasound images : rectus abdominis (RA) , external oblique, internal oblique, transversus abdominis, rectus femoris, vastus intermedius (VI), vastus lateralis (VL), vastus medialis (VM), tibialis anterior (TA), gastrocnemius (Gas), and soleus (Sol). The MT and EI values of these muscles were compared between stroke survivors and healthy older adults. Results : The MT values of the VL, VM, and RA on the non-paretic sides were significantly higher and those of the TA, Gas, and Sol on the paretic sides were significantly lower in the stroke survivors than in the healthy older adults (P < 0.05). The EI values of the VI, VL, VM, TA on the paretic sides and those of the Gas on both the paretic and non-paretic sides were significantly higher in the stroke survivors than in the healthy older adults (P < 0.05). Conclusion : Stroke survivors seem to develop muscle hypertrophy of the non-paretic thigh muscles owing to a compensatory strategy. In addition, the lower-leg muscles on the paretic side of stroke survivors tend to show both quantitative and qualitative muscle changes.

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“…A single examiner (H.M.) with extensive training in US measurement conducted all measurements. It was reported that the intraclass correlation coefficients (1, 1) of MT and RF EI were 0.98 and 0.94, respectively (n = 13, 26 limbs) [20].…”

Section: Ultrasonographic Assessmentmentioning

confidence: 93%

Quadriceps Thickness and Echo Intensity Predict Gait Independence in Individuals with Severe and Mild Hemiparetic Stroke

Maeda

Imada²,

Ishida

et al. 2020

Eur Neurol

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Introduction: Smaller muscle size and higher adipose tissue ratio of the quadriceps femoris are often observed after stroke. However, it is unclear whether muscle size and the intramuscular fat ratio of the quadriceps measured with ultrasonography (US) reflect gait independence in individuals with mild or severe hemiparetic stroke. Objective: The present study was performed to examine the relationships of gait independence with muscle thickness (MT) and echo intensity (EI) of the quadriceps femoris in individuals with hemiparesis after stroke. Methods: We examined 43 individuals with hemiparetic stroke. We assessed functional independence measure (FIM) gait scores and measured thickness and EI of the quadriceps using US. The relationships of FIM gait scores with MT and EI were examined using Spearman’s correlation coefficients in mild (n = 21) and severe (n = 22) hemiparetic stroke groups. Results: In the mild hemiparetic group, FIM gait scores were correlated with paretic limb MT (rho = 0.60, p < 0.01) and EI (rho = −0.57, p < 0.01). In the severe hemiparetic group, FIM gait scores were correlated with paretic limb MT (rho = 0.67, p < 0.01) and EI (rho = −0.43, p < 0.05), as well as non-paretic limb MT (rho = 0.86, p < 0.01) and EI (rho = −0.56, p < 0.01). Conclusions: Quadriceps thickness and EI were associated with the degree of gait independence. Atrophy and increased intramuscular fat of the quadriceps may be limiting factors for achieving gait independence.

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Relationship of Quadriceps Muscle Thickness with Motor Paralysis and Muscle Echo Intensity in Post-Stroke Patients

Cited by 12 publications

References 48 publications

Comparison of muscle quality and functional capacity between Japanese and Brazilian older individuals

Comparison of muscle quality and functional capacity between Japanese and Brazilian older individuals

Differences in muscle thickness and echo intensity between stroke survivors and age- and sex-matched healthy older adults

Quadriceps Thickness and Echo Intensity Predict Gait Independence in Individuals with Severe and Mild Hemiparetic Stroke

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