Relationship of Prostate-Specific Antigen and Prostate Volume in Korean Men with Biopsy-Proven Benign Prostatic Hyperplasia

Relationships between total/free prostate-specific antigen and prostate volume in Chinese men with biopsy-proven benign prostatic hyperplasia

“…Some have reported that the cellular composition of BPH in the prostates of American and Chinese men is different [14,15], and this difference also exists among white American, black American, and Japanese men [16], resulting in racial differences in PSA, PSA density, and the incidence of clinical BPH. The slope of linear regression of PSA and PV was 3.68 in Korean men with biopsy-proven BPH reported by Lee et al [11], higher than in white men reported by Hochberg et al [7]. This difference agrees with recent data reported by Chang et al [10] from their series of Taiwanese men.…”

“…In patients with LUTS and clinical BPH, the correlation coefficient seems to be slightly higher [13]. Selection of patients in our study was similar to that in previous reports [10,11], so the difference may be attributed to the racial difference rather than selection bias. Some have reported that the cellular composition of BPH in the prostates of American and Chinese men is different [14,15], and this difference also exists among white American, black American, and Japanese men [16], resulting in racial differences in PSA, PSA density, and the incidence of clinical BPH.…”

“…It has been shown that serum PSA correlates well with PV and PSA has been suggested for estimation of prostate volume in patients with symptomatic and pathologically confirmed BPH [6,7]. Recent studies which have included Asian men showed that the PSA-PV relationship appeared to be different across different races [9][10][11]. To the best of our knowledge, this study is the first to examine the relationship between PSA and PV in Chinese men.…”

“…Hochberg et al [7] first reported their series of American men with correlation coefficients of 0.39. Other studies that investigated Asian men also reported correlation coefficients of 0.37-0.41 [10][11][12]. In patients with LUTS and clinical BPH, the correlation coefficient seems to be slightly higher [13].…”

A novel equation and nomogram including body weight for estimating prostate volumes in men with biopsy-proven benign prostatic hyperplasia

“…Serum PSA has been accepted as a proxy parameter for TPV in different populations with similar results. [18][19][20][21][22][23] The serum PSA-TPV relationship curve in the current study was somewhat similar to those in previous studies in Asian populations. 22,23 Therefore, we believe that our data can be considered representative for Asian populations.…”