Relationship of Obstructive Sleep Apnoea and Metabolic Syndrome: A Study in a South Indian Population

Joshi, Harshal Satish; Arjun, P.; Matthewa, Thomas

doi:10.5958/0974-0155.2016.00005.x

Cited by 1 publication

(3 citation statements)

References 42 publications

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“…However a retrospective study from Mumbai, Maharashtra with 130 patients showed a prevalence of 66% for hypertension which is similar to our findings . [23][24][25] This reveals that although there is a variability in the prevalence of hypertension in patients with significant OSAS among various studies but most studies including ours have demonstrated a increased prevalence of hypertension in patients with moderate to severe OSAS when compared to prevalence in the community which is estimated to be 20% -30%. 26…”

Section: Hypertensionmentioning

confidence: 59%

“…Almost all studies have shown obesity to be very prevalent in patients with OSAS. [23][24][25] In this study 93.5% (115) patients with moderate or severe OSAS were obese making it the most common co morbidity to be associated with OSAS.…”

Section: Obesitymentioning

confidence: 63%

“…Again the prevalence of diabetes in our group was similar to the study from Mumbai ,Maharashtra by Utpat K et al which showed a prevalence of 44% in their group. [23][24][25]…”

Section: Diabetesmentioning

confidence: 99%

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Clinical profile of patients with moderate to severe obstructive sleep apnea syndrome in a centre from South Kerala

Ninan¹,

S²,

Balachandran³

et al. 2020

IJIRM

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Obstructive sleep apnea syndrome (OSAS), a common but under-recognized sleep-related breathing disorder (SRBD) which is associated with significant morbidity and increased mortality. The aim of this study done in South Kerala was to assess the clinical profile and comorbidities of patients with moderate to severe form of OSAS Materials and Methods: Patients included in the study were from a speciality sleep clinic and had symptoms of OSAS or risk factors for significant sleep apnea. They underwent a supervised polysomnography (PSG) with a portable equipment at home after history taking, relevant clinical evaluation, and pre-requisite workup. Results: One hundred and forty patients were included in the study and 87.9% (123) of the patients were detected to have moderate or severe OSAS (Apnea Hypopnea Index AHI>15 episodes/hour), 81 % (100) of these patients with significant ( moderate or severe) sleep apnea were males having a mean age of 47.9 years, mean body mass index of 33.6 kg/m 2 and an average neck circumference of 41.2 cm. 80% of patients with moderate to severe OSAS were between the ages of 31-60 years.61.7% and 41% of patients with significant OSAS had hypertension and diabetes respectively. Body mass index and neck circumference had a direct correlation with the severity of OSAS. Statistical analysis: The data was analysed using SPSS 20.0. The factors and co-morbidities associated with OSAS were analysed using Chi-square tests and Independent Sample t-tests. Pearson's correlation coefficient and a linear regression model was made to find out the possible predictors for AHI Scores and a p value of less than 0.05 was taken as significant. Conclusion: Our study on the clinical profile of patients with obstructive sleep apnea syndrome from a centre in South Kerala shows male predilection, frequent association with obesity and cardiovascular comorbidities such as hypertension and diabetes.

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Section: Hypertensionmentioning

confidence: 59%

Section: Obesitymentioning

confidence: 63%