Relationship of neuropsychological status to everyday functioning in healthy and chronically Ill persons

McSweeny, A. John; Grant, Igor; Heaton, Robert K.; Prigatano, George P.; Adams, Kenneth M.

doi:10.1080/01688638508401260

Cited by 72 publications

(19 citation statements)

References 18 publications

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“…Bedard et al (1991) noticed that in subjects with OSA, a poorer performance in the Purdue Pegboard Test was associated with higher levels of apnea. McSweeney et al (1985) obtained similar findings among subjects with COPD using the FTT. However, results in this area are inconclusive (Grant et al, 1987;Stuss et al, 1997).…”

Section: Possible Permanent Dysfunctionssupporting

confidence: 85%

Neuropsychological Functioning Associated with High-Altitude Exposure

et al. 2004

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This article focuses on neuropsychological functioning at moderate, high, and extreme altitude. This article summarizes the available literature on respiratory, circulatory, and brain determinants on adaptation to hypoxia that are hypothesized to be responsible for neuropsychological impairment due to altitude. Effects on sleep are also described. At central level, periventricular focal damages (leuko-araiosis) and cortical atrophy have been observed. Frontal lobe and middle temporal lobe alterations are also presumed. A review is provided regarding the effects on psychomotor performance, perception, learning, memory, language, cognitive flexibility, and metamemory. Increase of reaction time and latency of P300 are observed. Reduced thresholds of tact, smell, pain, and taste, together with somesthetic illusions and visual hallucinations have been reported. Impairment in codification and short-term memory are especially noticeable above 6,000 m. Alterations in accuracy and motor speed are identified at lower altitudes. Deficits in verbal fluency, language production, cognitive fluency, and metamemory are also detected. The moderating effects of personality variables over the above-mentioned processes are discussed. Finally, methodological flaws found in the literature are detailed and some applied proposals are suggested.

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Section: Possible Permanent Dysfunctionssupporting

confidence: 85%

Neuropsychological Functioning Associated with High-Altitude Exposure

et al. 2004

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“…Similar findings of decreased quality of life associated with cognitive impairments are found in stroke patients (Kwa et al, 1996a(Kwa et al, , 1996b, in ICU survivors following multiple trauma (Thiagarajan & Miranda, 1995), following traumatic brain injury (Warren et al, 1996), HIV (Osowiecki et al, 2000), carbon monoxide poisoning , and COPD (McSweeny & Labuhn, 1996). For example impaired executive function significantly correlated with poor life functioning in COPD patients (McSweeny et al, 1985).…”

Section: Relationship Between Quality Of Life and Cognitive Sequelaementioning

confidence: 99%

Quality of life, emotional, and cognitive function following acute respiratory distress syndrome

Hopkins

Weaver

Chan

et al. 2004

J Int Neuropsychol Soc

161

129

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Acute Respiratory Distress Syndrome (ARDS) is characterized by lung injury and hypoxemia, has a high mortality rate, and is associated with significant morbidity including cognitive and emotional sequelae and decreased quality of life. There is limited information regarding which of these factors are associated with decreased quality of life. This study assessed the relationships between quality of life, cognitive and emotional function in ARDS survivors at 1-year post-hospital discharge. Sixty-six ARDS survivors were administered a battery of neuropsychological tests, measures of emotional function and quality of life 1 year post-hospital discharge. At 1 year 45% of the ARDS patients had cognitive sequelae and 29% had mild to moderate symptoms of depression and anxiety. Depression, anxiety, and intensive care unit length of stay were significantly correlated with decreased quality of life. Cognitive impairments did not correlate with decreased quality of life. Illness severity and emotional function, but not cognitive sequelae, are associated with decreased quality of life 1 year following ARDS. ARDS is common and may result in significant cognitive and emotional morbidity and decreased quality of life. (JINS, 2004(JINS, , 10, 1005(JINS, -1017

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“…Except for Delayed Word Recall in men, these results held in the extended multivariable models which included control for smoking status. Chronic obstructive pulmonary disease has been associated with decrements in memory, psychomotor speed and verbal skills [44]; these decrements have also been found in clinic-based studies of persons with mild hypoxemia, with more extensive hypoxemia associated with more severe cognitive deficits [45][46][47].…”

Section: Correlates Of Cognitive Function In the Aric Studymentioning

confidence: 99%

Correlates of Cognitive Function in Middle-Aged Adults

Cerhan

Folsom

Mortimer³

et al. 1998

Gerontology

237

131

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The Atherosclerosis Risk in Communities Study administered cognitive function tests to more than 14,000 middle-aged adults in 1990–1992. The battery included the Delayed Word Recall test, the Digit Symbol Subtest of the Wechsler Adult Intelligence Scale-Revised, and the Controlled Oral Word Association (Word Fluency) test. Test performance was correlated positively with education level, negatively with age, was better in women than in men, and better in managers/professionals compared with other occupations. After controlling for these factors, race and community, the findings most consistent for both sexes were that Delayed Word Recall was negatively associated with depressive symptoms, diabetes, and fibrinogen level; the Digit Symbol Subtest was associated with marital status, negatively associated with depressive symptoms, smoking status, fibrinogen level, and carotid intima-media thickness, and positively associated with alcohol drinking and FEV₁; and the Word Fluency test was positively associated with marital status, alcohol drinking, sports participation, and FEV₁. Most of these cross-sectional results were in the predicted direction and have biologic plausibility, but mean differences between extreme categories were small (generally on the order of 0.1 to 0.2 of a standard deviation). Longitudinal study is warranted to evaluate whether small differences in middle-age lead to larger, clinically meaningful deficits with aging.

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Relationship of neuropsychological status to everyday functioning in healthy and chronically Ill persons

Cited by 72 publications

References 18 publications

Neuropsychological Functioning Associated with High-Altitude Exposure

Neuropsychological Functioning Associated with High-Altitude Exposure

Quality of life, emotional, and cognitive function following acute respiratory distress syndrome

Correlates of Cognitive Function in Middle-Aged Adults

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