Relationship of heart rate turbulence, heart rate variability and the number of ventricular premature beats in patients with mitral valve prolapse and non-significant regurgitation

Anterior Mitral Valve Length is Associated with Ventricular Tachycardia in Patients with Classical Mitral Valve Prolapse

“…Ventricular arrhythmias are known to be common in patients with mitral valve prolapse (MVP) 1–3 . Today, noninvasive electrocardiographic methods (heart rate variability [HRV], QT dispersion [QTD], and late potentials) are widely used to determine the risk of developing serious ventricular arrhythmias 4–19 . Echocardiographic correlates of ventricular tachycardia (VT) were also defined in different studies.…”

“…[1][2][3] Today, noninvasive electrocardiographic methods (heart rate variability [HRV], QT dispersion [QTD], and late potentials) are widely used to determine the risk of developing serious ventricular arrhythmias. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Echocardiographic correlates of ventricular tachycardia (VT) were also defined in different studies. In these studies, the degree of mitral regurgitation (MR) and the degree of the prolapsus were shown as inde-pendent predictors of VT. 16,19 However, in some other studies MR was not an independent predictor of ventricular arrhythmias.…”

Circadian variation of heart rate turbulence and the number of ventricular premature beats in patients with mitral valve prolapse

“…Several studies have shown that HRT impairment reflects cardiac autonomic dysfunction, in particular, impaired baroreflex sensitivity and reduced parasympathetic activity [3]. In our previous study, no significant correlations were found between the number of VPCs and HRT parameters in patients with MVP [4]. However, there are fluctuations in autonomic tone in a day.…”

Electrocardiographic Changes in Mitral Valve Prolapse Syndrome

“…It seems impaired autonomic function is responsible for postural hemodynamic variations, cardiac arrhythmias and syncope in patients with MVP syndrome. 19,20 It is not clearly known which mechanisms- either arrhythmogenic, neurohumoral or hemodynamic- leads to sudden death in this group of patients. 15 Some pathophysiological studies demonstrated role of the vascular malformation and its effects on the cardiac chambers in sudden death in MVP.…”